Evidence map›Paper›PMID 26498192›Full record

ReviewFungal genetics and biology : FG & B2016

The circadian system as an organizer of metabolism.

Jennifer M Hurley, Jennifer J Loros, Jay C Dunlap

Abstract readReview
In one paragraph

Review in Fungal genetics and biology : FG & B, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers.

0numbers the graph read from it
0cells of the map it votes in
20citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

20 citing papers in PubMed.

  1. Article
  2. Uncovering the circadian transcriptome ofProceedings. Biological sciences · 2024
    Article
  3. Article
  4. Article
  5. Article
  6. Article
  7. Review
  8. Review
  9. Review
  10. Article
  11. Article
  12. Article
  13. Article
  14. Regulation of plant cell wall degradation by light inFungal biology and biotechnology · 2018
    Review
  15. Article
  16. Article
  17. Review
  18. Review
  19. Article
  20. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Jennifer M HurleyDepartment of Biological Sciences, Rensselaer Polytechnic Institute, Troy, NY 12180, USA. Electronic address: hurlej2@rpi.edu.
Jennifer J LorosDepartment of Biochemistry, Geisel School of Medicine at Dartmouth, Hanover, NH 03755, USA.
Jay C DunlapDepartment of Genetics, Geisel School of Medicine at Dartmouth, Hanover, NH 03755, USA.

Funding

Genetic and Molecular Dissection of the Neurospora ClockR35GM118021 · NIGMS · DARTMOUTH COLLEGE · PI Jay C. Dunlap · 2016 to 2026
$7.3M
Identification and Analysis of Circadian Clock-Controlled GenesR01GM083336 · NIGMS · DARTMOUTH COLLEGE · PI LOROS, JENNIFER J. · 2008 to 2015
$5.7M
GENETIC AND MOLECULAR DISSECTION OF THE NEUROSPORA CLOCKR01GM034985 · NIGMS · DARTMOUTH COLLEGE · PI DUNLAP, JAY C. · 1986 to 2015
$5.7M
GENETIC AND MOLECULAR DISSECTION OF THE NEUSPORA CLOCKR37GM034985 · NIGMS · DARTMOUTH COLLEGE · PI DUNLAP, JAY C · 1998 to 2007
$4.4M
Identification and Analysis of Circadian Clock-Controlled GenesR35GM118022 · NIGMS · DARTMOUTH COLLEGE · PI LOROS, JENNIFER J. · 2016 to 2021
$3.7M
NIGMS NIH HHS GM083336NIGMS NIH HHS GM 34985NIGMS NIH HHS R01 GM034985NIGMS NIH HHS R01 GM083336NIGMS NIH HHS R35 GM118021NIGMS NIH HHS R35 GM118022NIGMS NIH HHS R37 GM034985
6 · The paper itself

Abstract

The regulation of metabolism by circadian systems is believed to be a key reason for the extensive representation of circadian rhythms within the tree of life. Despite this, surprisingly little work has focused on the link between metabolism and the clock in Neurospora, a key model system in circadian research. The analysis that has been performed has focused on the unidirectional control from the clock to metabolism and largely ignored the feedback from metabolism on the clock. Recent efforts to understand these links have broken new ground, revealing bidirectional control from the clock to metabolism and vise-versa, showing just how strongly interconnected these two cellular systems can be in fungi. This review describes both well understood and emerging links between the clock and metabolic output of fungi as well as the role that metabolism plays in influencing the rhythm set by the clock.

Indexed as

Circadian ClocksCircadian RhythmCLOCK ProteinsFeedback, PhysiologicalFungal ProteinsFungiMetabolic Networks and PathwaysCLOCK ProteinsFungal ProteinsCircadianClock-controlled genesMetabolismNeurosporaOutput

Identifiers

PMID26498192
PMCPMC4818683

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.