Evidence map›Paper›PMID 26498186›Full record

ArticleVirchows Archiv : an international journal of pathology2016

Individualized medicine and demographic change as determining workload factors in pathology: quo vadis?

Arne Warth, Albrecht Stenzinger, Mindaugas Andrulis, Werner Schlake, Gisela Kempny, Peter Schirmacher, Wilko Weichert

Abstract read
PubMed Publisher
In one paragraph

Article in Virchows Archiv : an international journal of pathology, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers.

0numbers the graph read from it
0cells of the map it votes in
16citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

16 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
  4. Publication productivity of pathology residents: a nationwide cohort study in France.Virchows Archiv : an international journal of pathology · 2025
    Article
  5. Review
  6. Review
  7. Article
  8. Article
  9. Article
  10. Article
  11. Number of pathologists in Germany: comparison with European countries, USA, and Canada.Virchows Archiv : an international journal of pathology · 2021
    Article
  12. Article
  13. Article
  14. Article
  15. Article
  16. Ki-67 expression in pulmonary tumors-reply.Translational lung cancer research · 2016
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Arne WarthInstitute of Pathology, University Hospital Heidelberg, INF 224, 69120, Heidelberg, Germany. arne.warth@med.uni-heidelberg.de.
Albrecht StenzingerInstitute of Pathology, University Hospital Heidelberg, INF 224, 69120, Heidelberg, Germany.
Mindaugas AndrulisInstitute of Pathology, University Hospital Heidelberg, INF 224, 69120, Heidelberg, Germany.
Werner SchlakeInstitute of Pathology, Gelsenkirchen, Germany.
Gisela KempnyInstitute of Pathology, Gelsenkirchen, Germany.
Peter SchirmacherInstitute of Pathology, University Hospital Heidelberg, INF 224, 69120, Heidelberg, Germany.
Wilko WeichertInstitute of Pathology, University Hospital Heidelberg, INF 224, 69120, Heidelberg, Germany.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The advent of individualized medicine with novel guidelines, extended quality assessment as well as intensified conventional, immunohistochemical, and molecular characterization of diseases has led to a substantial increase of pathologists' workload. Furthermore, in industrialized countries, we are facing the challenges of demographic change with an aging population. This raises the question of how pathology will be affected by these developments in the future. We extracted German population data and data on the number of board-certified physicians and pathologists from official sources. These data were reviewed in the light of data on caseload, case complexity, auxiliary diagnostic procedures, and matching patient data from a large German pathology department serving as a sector independent regional service provider. The refinement of diagnostic procedures over the last decade has resulted in a 60 % increase in slide numbers per case, doubling of immunohistochemistry procedures, and more than tripling of molecular analyses. Correlation of this development to demographics suggests that an aging population will further increase the caseload and case complexity in the coming decades since patient age is tightly linked to both parameters. This development is currently not accompanied by a sufficient increase in the number of pathologists. Our data point toward an imbalance between the increase in pathology workload and the number of pathologists. Extrapolations suggest a further aggravation of this development in the future. Thus, healthcare systems need to address this problem urgently in order to cope with these challenges.

Indexed as

GermanyHumansPathology, ClinicalPrecision MedicineWorkforceWorkloadDemographic changeEducationHealth carePathologyWorkload

Identifiers

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.