Evidence map›Paper›PMID 26498173›Full record

Trial reportNicotine & tobacco research : official journal of the Society for Research on Nicotine and Tobacco2016

Predictive Validity of a Cigarette Purchase Task in a Randomized Controlled Trial of Contingent Vouchers for Smoking in Individuals With Substance Use Disorders.

James Mackillop, Cara M Murphy, Rosemarie A Martin, Monika Stojek, Jennifer W Tidey, Suzanne M Colby, Damaris J Rohsenow

Registry-linked trialOpen access · greenAbstract readRandomized Controlled Trial
In one paragraph

Trial report in Nicotine & tobacco research : official journal of the Society for Research on Nicotine and Tobacco, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT00807742 (Contingent Vouchers for Smoking in Substance Abusers as Adjunct to Nicotine Patch), which is not on this map. Cited by 52 papers, 3 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
52citing papers in PubMed, 3 pooled it
5.7field-weighted citation impact, top 4% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT00807742 nacompletednot on this map

Contingent Vouchers for Smoking in Substance Abusers as Adjunct to Nicotine Patch

TypeinterventionalSponsorBrown UniversityRan2008 to 2014Enrolled340ConditionsSubstance AbuseArmsNicotine Replacement Treatment (NRT), Brief Advice, Contingency Management, Non-Contingent Reinforcement
3 · Its place in the literature

Who cites it

52 citing papers in PubMed, 3 syntheses or guidelines pooled it, 117 citations in OpenAlex.

  1. Financial Incentives for Substance Abstinence: A Systematic Review and Meta-analysis.Nicotine & tobacco research : official journal of the Society for Research on Nicotine and Tobacco · 2025
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  4. Do lab-based assessments of pretreatment smoking reinforcement and cue-specific craving predict smoking cessation with varenicline?Psychology of addictive behaviors : journal of the Society of Psychologists in Addictive Behaviors · 2025
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  17. Blood Nicotine Predicts the Behavioral Economic Abuse Liability of Reduced-Nicotine Cigarettes.Nicotine & tobacco research : official journal of the Society for Research on Nicotine and Tobacco · 2022
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 3 institutions in 2 countries.

James MackillopPeter Boris Centre for Addictions Research, McMaster University/St. Joseph's Healthcare Hamilton, Hamilton, ON, Canada; Center for Alcohol and Addiction Studies, Brown University, Providence, RI; Department of Psychology, University of Georgia, Athens, GA;
Cara M MurphyCenter for Alcohol and Addiction Studies, Brown University, Providence, RI; Department of Psychology, University of Georgia, Athens, GA;
Rosemarie A MartinCenter for Alcohol and Addiction Studies, Brown University, Providence, RI;
Monika StojekDepartment of Psychology, University of Georgia, Athens, GA;
Jennifer W TideyCenter for Alcohol and Addiction Studies, Brown University, Providence, RI;
Suzanne M ColbyCenter for Alcohol and Addiction Studies, Brown University, Providence, RI;
Damaris J RohsenowCenter for Alcohol and Addiction Studies, Brown University, Providence, RI; Research Service, Providence Veterans Affairs Medical Center, Providence, RI Damaris_Rohsenow@brown.edu.
Brown University · USUniversity of Georgia · USMcMaster University · CA

Funding

Contingent Vouchers for Smoking in Substance Abusers as Adjunct to Nicotine PatchR01DA023995 · NIDA · BROWN UNIVERSITY · PI ROHSENOW, DAMARIS J. · 2008 to 2012
$3.0M
NIDA NIH HHS 1R01 DA023995NIDA NIH HHS R01 DA023995
6 · The paper itself

Abstract

introductionA cigarette purchase task (CPT) is a behavioral economic measure of the reinforcing value of smoking in monetary terms (ie, cigarette demand). This study investigated whether cigarette demand predicted response to contingent monetary rewards for abstinence among individuals with substance use disorders. It also sought to replicate evidence for greater price sensitivity at whole-dollar pack price transitions (ie, left-digit effects).

methodsParticipants (N = 338) were individuals in residential substance use disorder treatment who participated in a randomized controlled trial that compared contingent vouchers to noncontingent vouchers for smoking abstinence. Baseline demand indices were used to predict number of abstinent days during the 14-day voucher period (after the reduction lead-in) and at 1 and 3 months afterward.

resultsDemand indices correlated with measures of smoking and nicotine dependence. As measured by elasticity, intensity and O max, higher demand significantly predicted fewer abstinent exhaled carbon monoxide readings during voucher period for individuals in the noncontingent vouchers condition. Breakpoint exhibited a trend-level association with abstinent exhaled carbon monoxide readings. Demand indices did not predict abstinence in the contingent vouchers group, and did not predict abstinence at 1- and 3-month follow-ups. Left-digit price transitions were associated with significantly greater reductions in consumption.

conclusionsThe association of cigarette demand with smoking behavior only in the group for whom abstinence was not incentivized indicates that CPT assesses the value of smoking more than the value of money per se and that vouchers counteract the effects of the intrinsic reinforcing value of cigarettes. Results provide initial short-term evidence of predictive validity for the CPT indices. IMPLICATIONS: This study provides the first evidence of the validity of the CPT for predicting early response to brief advice for smoking cessation plus nicotine replacement in smokers with substance dependence. However, demand for cigarettes did not predict voucher-based treatment response, indicating that incentives serve as a powerful motivator not to smoke that acts in opposition to the intrinsic reinforcing value of cigarettes and that the indices reflect the value of smoking more than the value of money per se.

Indexed as

Smoking CessationTobacco Use DisorderAdultFemaleHumansMaleMiddle AgedMotivationRewardSmokingSubstance-Related Disorders

Identifiers

PMID26498173
PMCPMC5896828
OpenAlexW1845463313

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.