Evidence map›Paper›PMID 26498040›Full record

ArticleChemical communications (Cambridge, England)2016

Asymmetric synthesis of 1H-pyrrol-3(2H)-ones from 2,3-diketoesters by combination of aldol condensation with benzilic acid rearrangement.

Qiang Sha, Hadi Arman, Michael P Doyle

Abstract read
In one paragraph

Article in Chemical communications (Cambridge, England), 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Qiang ShaSchool of Chemical Engineering, Nanjing University of Science and Technology, Xiao Ling Wei 200, Nanjing 210094, P. R. China and Department of Chemistry, The University of Texas at San Antonio, San Antonio, Texas 78249, USA. michael.doyle@utsa.edu.
Hadi ArmanDepartment of Chemistry, The University of Texas at San Antonio, San Antonio, Texas 78249, USA. michael.doyle@utsa.edu.
Michael P DoyleDepartment of Chemistry, The University of Texas at San Antonio, San Antonio, Texas 78249, USA. michael.doyle@utsa.edu.

Funding

RCMI Center for Interdiscplinary Health Research CIHRG12MD007591 · NIMHD · UNIVERSITY OF TEXAS SAN ANTONIO · PI PERRY, GEORGE · 2012 to 2016
$10.4M
CHIRAL CATALYSTS FOR ENANTIOSELECTIVE SYNTHESESR37GM046503 · NIGMS · UNIV OF MARYLAND, COLLEGE PARK · PI DOYLE, MICHAEL PATRICK · 2003 to 2012
$2.6M
NIGMS NIH HHS R37 GM046503NIMHD NIH HHS G12 MD007591NIMHD NIH HHS G12MD007591
6 · The paper itself

Abstract

An efficient two-step protocol for the asymmetric synthesis of 1H-pyrrol-3(2H)-one derivatives in 99% ee from conveniently accessed 2,3-diketoesters has been developed.

Indexed as

AldehydesBenzilatesEsterificationKetonesModels, MolecularPyrroles3-hydroxybutanalAldehydesBenzilatesKetonesPyrroles

Identifiers

PMID26498040
PMCPMC4679521

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.