Evidence map›Paper›PMID 26497666›Full record

ReviewEuropean radiology2016

Incidentally detected non-palpable testicular tumours in adults at scrotal ultrasound: impact of radiological findings on management Radiologic review and recommendations of the ESUR scrotal imaging subcommittee.

Laurence Rocher, Parvati Ramchandani, Jane Belfield, Michele Bertolotto, Lorenzo E Derchi, Jean Michel Correas, Raymond Oyen, Athina C Tsili, Ahmet Tuncay Turgut, Vikram Dogra and 3 more

Open access · greenAbstract readReview
PubMed Publisher
In one paragraph

Review in European radiology, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 42 papers, 3 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
42citing papers in PubMed, 3 pooled it
6.5field-weighted citation impact, top 3% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

42 citing papers in PubMed, 3 syntheses or guidelines pooled it, 105 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors at 12 institutions in 6 countries.

Laurence RocherHopitaux Paris Sud, APHP, site Bicêtre, 78 avenue du Général Leclerc, 94270, Le Kremlin Bicêtre, France. laurence.rocher@aphp.fr.
Parvati RamchandaniPerelman School of Medicine, University of Pennsylvania, 3400 Spruce Street, Philadelphia, PA, 19104, USA.
Jane BelfieldRoyal Liverpool University Hospital, Prescot Street, Liverpool, L7 8XP, UK.
Michele BertolottoUco di Radiologia Dell 'Universita' di Trieste, Strada di Fiume 447, Trieste, Italy.
Lorenzo E DerchiUniversita di Genova, Largo R. Benzi, 8, Genova, Italy.
Jean Michel CorreasUniversité Paris Descartes, Hôpital Necker, APHP, Institut Langevin, 149 rue de Sèvres, Paris 15, Paris, France.
Raymond OyenRadiology, University Hospital Leuven, UZ Herestraat 49, box 7003 54, 3000, Leuven, Belgium.
Athina C TsiliUniversity of Ioannina, Pl. Pargis, 2, Ionnina, 45332, Greece.
Ahmet Tuncay TurgutRadiology, Sokak Huner Sitesi No: 18/30, 25. Cadde 362, Ankara, 6530, Turkey.
Vikram DograDepartment of Imaging Sciences, University of Rochester School of Medicine and Dentistry, 601 Elmwood Ave, Box 648, Rochester, NY, USA.
Karim FizaziUniversité Paris Sud, Institut Gustave Roussy, 114 rue Edouard Vaillant, 94805, Villejuif, France.
Simon FreemanPlymouth Hospitals NHS Trust, Devon, UK.
Jonathan RichenbergRoyal Sussex County Hospital Brighton and Brighton and Sussex Medical School, East Sussex, UK.
Assistance Publique – Hôpitaux de Paris · FRBicêtre Hospital · FRBrighton and Sussex Medical School · GBInstitut Gustave Roussy · FRKU Leuven · BEPlymouth Hospital · GBRoyal Liverpool University Hospital · GBUniversity of Genoa · ITUniversity of Ioannina · GRUniversity of Pennsylvania · USUniversity of Rochester · USUniversity of Trieste · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectivesThe increasing detection of small testicular lesions by ultrasound (US) in adults can lead to unnecessary orchiectomies. This article describes their nature, reviews the available literature on this subject and illustrates some classical lesions. We also suggest recommendations to help characterization and management.

methodsThe ESUR scrotal imaging subcommittee searched for original and review articles published before May 2015 using the Pubmed and Medline databases. Key words used were 'testicular ultrasound', 'contrast-enhanced sonography', 'sonoelastography', 'magnetic resonance imaging', 'testis-sparing surgery', 'testis imaging', 'Leydig cell tumour', 'testicular cyst'. Consensus was obtained amongst the members of the subcommittee, urologist and medical oncologist.

resultsSimple cysts are frequent and benign, and do not require follow up or surgery. Incidentally discovered small solid testicular lesions detected are benign in up to 80 %, with Leydig cell tumours being the most frequent. However, the presence of microliths, macrocalcifications and hypoechoic areas surrounding the nodule are findings suggestive of malignant disease.

conclusionAsymptomatic small testicular lesions found on ultrasound are mainly benign, but findings such as microliths or hypoechoic regions surrounding the nodules may indicate malignancy. Colour Doppler US remains the basic examination for characterization. The role of newer imaging modalities in characterization is evolving. KEY POINTS: • Characterization of testicular lesions is primarily based on US examination. • The role of MRI, sonoelastography, contrast-enhanced ultrasound is evolving. • Most small non-palpable testicular lesions seen on ultrasound are benign simple cysts. • Leydig cell tumours are the most frequent benign lesions. • Associated findings like microliths or hypoechoic regions may indicate malignancy.

Indexed as

Incidental FindingsAdultEuropeHumansMaleScrotumSocieties, MedicalTesticular NeoplasmsUltrasonographyColour Doppler ultrasoundContrast-enhanced sonographyMagnetic resonance ImagingSonoelastographyTesticular tumours

Identifiers

PMID26497666
OpenAlexW1853367796

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.