Evidence map›Paper›PMID 26497609›Full record

ArticleOsteoarthritis and cartilage2016

Measures of hip morphology are related to development of worsening radiographic hip osteoarthritis over 6 to 13 year follow-up: the Johnston County Osteoarthritis Project.

A E Nelson, J L Stiller, X A Shi, K M Leyland, J B Renner, T A Schwartz, N K Arden, J M Jordan

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Osteoarthritis and cartilage, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 28 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
28citing papers in PubMed, 2 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

28 citing papers in PubMed, 2 syntheses or guidelines pooled it.

  1. Pooled it
  2. Pooled it
  3. Article
  4. Review
  5. Article
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  7. Article
  8. Review
  9. Epidemiology of Hip Osteoarthritis: The Johnston County Osteoarthritis Project.HSS journal : the musculoskeletal journal of Hospital for Special Surgery · 2023
    Review
  10. Machine Learning-Derived Acetabular Dysplasia and Cam Morphology Are Features of Severe Hip Osteoarthritis: Findings From UK Biobank.Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research · 2022
    Article
  11. Epidemiology of osteoarthritis.Osteoarthritis and cartilage · 2022
    Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

A E NelsonThurston Arthritis Research Center, University of North Carolina at Chapel Hill, Chapel Hill, NC, USA; Department of Medicine, University of North Carolina at Chapel Hill, Chapel Hill, NC, USA. Electronic address: aenelson@med.unc.edu.
J L StillerThurston Arthritis Research Center, University of North Carolina at Chapel Hill, Chapel Hill, NC, USA. Electronic address: jamie_stiller@med.unc.edu.
X A ShiSAS Institute, Inc, Cary, NC, USA. Electronic address: amy.shi@sas.com.
K M LeylandNIHR Musculoskeletal Biomedical Research Unit and Arthritis Research UK Centre for Sport, Exercise, and Osteoarthritis, University of Oxford, Oxford, UK. Electronic address: kirsten.leyland@ndorms.ox.ac.uk.
J B RennerThurston Arthritis Research Center, University of North Carolina at Chapel Hill, Chapel Hill, NC, USA; Department of Radiology, University of North Carolina at Chapel Hill, Chapel Hill, NC, USA. Electronic address: jordan_renner@med.unc.edu.
T A SchwartzThurston Arthritis Research Center, University of North Carolina at Chapel Hill, Chapel Hill, NC, USA; Department of Biostatistics, Gillings School of Global Public Health, University of North Carolina at Chapel Hill, Chapel Hill, NC, USA. Electronic address: tschwart@email.unc.edu.
N K ArdenNIHR Musculoskeletal Biomedical Research Unit and Arthritis Research UK Centre for Sport, Exercise, and Osteoarthritis, University of Oxford, Oxford, UK. Electronic address: nigel.arden@ndorms.ox.ac.uk.
J M JordanThurston Arthritis Research Center, University of North Carolina at Chapel Hill, Chapel Hill, NC, USA; Department of Medicine, University of North Carolina at Chapel Hill, Chapel Hill, NC, USA; Department of Epidemiology, Gillings School of Global Public Health, University of North Carolina at Chapel Hill, Chapel Hill, NC, USA; Department of Orthopaedics, University of North Carolina at Chapel Hill, Chapel Hill, NC, USA. Electronic address: joanne_jordan@med.unc.edu.

Funding

Project 3P60AR049465 · NIAMS · UNIV OF NORTH CAROLINA CHAPEL HILL · PI JORDAN, JOANNE M. · 2003 to 2008
$6.0M
Women's knee motion patterns in functional activitiesP60AR030701 · NIAMS · UNIVERSITY OF NORTH CAROLINA CHAPEL HILL · PI LEE, GRETA M · 1986 to 2001
$1.9M
Variations in Hip Morphology: Frequency and Impact on Osteoarthritis OutcomesK23AR061406 · NIAMS · UNIV OF NORTH CAROLINA CHAPEL HILL · PI NELSON, AMANDA E · 2011 to 2015
$668k
Arthritis Research UKNHLBI NIH HHS HHSN268201000019CNIAMS NIH HHS BAA-NHLBI-AR-10-06NIAMS NIH HHS K23 AR061406NIAMS NIH HHS P60 AR030701NIAMS NIH HHS P60 AR049465NIAMS NIH HHS P60AR30701
6 · The paper itself

Abstract

objectivesWe sought to describe the effect of alterations in hip morphology with respect to worsening hip OA in a community-based sample including African American (AA) and white men and women.

methodsThis nested case-control study defined case hips as Kellgren Lawrence grade (KLG) <3 on baseline supine pelvis radiographs and KLG ≥3 or THR for OA at the 1st or 2nd follow-up visit (mean 6 and 13 years, respectively); control hips had KLG <3 at both visits, with gender/race distribution similar to cases. Hip morphology was assessed using HipMorf software (Oxford, UK). Descriptive means and standard errors were obtained from generalized estimating equation (GEE) models. Sex-stratified GEE regression models (accounting for within-person correlation), adjusted for age, race, BMI, and side were then employed.

resultsA total of 120 individuals (239 hips; 71 case/168 control) were included (25% male, 26% AA, mean age 62 years, BMI 30 kg/m(2)). Case hips tended to have greater baseline AP alpha angles, smaller minimum joint space width (mJSW) and more frequent triangular index signs. Adjusted results among men revealed that higher AP alpha angle, Gosvig ratio, and acetabular index were positively associated with case hips; coxa profunda was negatively associated. Among women, greater AP alpha angle, smaller mJSW, protrusio acetabuli, and triangular index sign were associated with case hips.

conclusionsWe confirmed an increased risk of worsening hip OA due to baseline features of cam deformity among men and women, as well as protrusio acetabuli among women, and provide the first estimates of these measures in AAs.

Indexed as

AgedBlack or African AmericanCase-Control StudiesDisease ProgressionFemaleFemoracetabular ImpingementFollow-Up StudiesHip JointHumansMaleMiddle AgedOsteoarthritis, HipRadiographySeverity of Illness IndexSex FactorsWhite PeopleFemoroacetabular impingementHip morphologyRace/sex differences

Identifiers

PMID26497609
PMCPMC4761268

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.