ArticleEnvironmental geochemistry and health2016
Chinese population exposure to triclosan and triclocarban as measured via human urine and nails.
Article in Environmental geochemistry and health, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 26 papers, 1 of them a synthesis that pooled it.
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Who cites it
26 citing papers in PubMed, 1 synthesis or guideline pooled it, 96 citations in OpenAlex.
- Effect of Maternal Triclosan Exposure on Neonatal Birth Weight and Children Triclosan Exposure on Children's BMI: A Meta-Analysis.Frontiers in public health · 2021Pooled it
- Modulation of immune gene expression profile in Labeo catla with chronic toxicity to emerging endocrine disruptors through a multiorgan approach.Scientific reports · 2025Article
- Interleukin 1β and interleukin 6 production in human immune cells is stimulated by the antibacterial compound Triclosan.Archives of toxicology · 2024Article
- The Potential for Genotoxicity, Mutagenicity and Endocrine Disruption in Triclosan and Triclocarban Assessed through a Combination of In Vitro Methods.Journal of xenobiotics · 2023Article
- Single-cell transcriptomic dissection of the cellular and molecular events underlying the triclosan-induced liver fibrosis in mice.Military Medical Research · 2023Article
- Facile Synthesis of ZnO-CeONanomaterials (Basel, Switzerland) · 2022Article
- The Presence of Triclosan in Human Hair Samples in Poland-A Pilot Study.International journal of environmental research and public health · 2022Article
- Environmental Exposure to Triclosan and Male Fecundity: A Prospective Study in China.Frontiers in public health · 2022Article
- Measurement of Urinary Triclocarban and 2,4-Dichlorophenol Concentration and Their Relationship with Obesity and Predictors of Cardiovascular Diseases among Children and Adolescents in Kerman, Iran.Journal of environmental and public health · 2022Article
- Prenatal Exposure to Triclocarban Impairs ESR1 Signaling and Disrupts Epigenetic Status in Sex-Specific Ways as Well as Dysregulates the Expression of Neurogenesis- and Neurotransmitter-Related Genes in the Postnatal Mouse Brain.International journal of molecular sciences · 2021Article
- Long-term exposure to triclosan increases migration and invasion of human breast epithelial cells in vitro.Journal of applied toxicology : JAT · 2021Article
- Benzothiazole-Containing Analogues of Triclocarban with Potent Antibacterial Activity.Antibiotics (Basel, Switzerland) · 2021Article
- The Different Facets of Triclocarban: A Review.Molecules (Basel, Switzerland) · 2021Review
- Evaluation of triclosan exposures on secretion of pro-inflammatory cytokines from human immune cells.Environmental toxicology and pharmacology · 2021Article
- A Review on the Fate of Legacy and Alternative Antimicrobials and Their Metabolites during Wastewater and Sludge Treatment.International journal of molecular sciences · 2020Review
- Disposition and metabolism of antibacterial agent, triclocarban, in rodents; a species and route comparison.Xenobiotica; the fate of foreign compounds in biological systems · 2020Article
- The prevalence and mechanism of triclosan resistance in Escherichia coli isolated from urine samples in Wenzhou, China.Antimicrobial resistance and infection control · 2020Article
- Triclocarban, Triclosan, Bromochlorophene, Chlorophene, and Climbazole Effects on Nuclear Receptors: AnEnvironmental health perspectives · 2020Article
- Triclocarban Disrupts the Epigenetic Status of Neuronal Cells and Induces AHR/CAR-Mediated Apoptosis.Molecular neurobiology · 2019Article
- Cross-sectional associations between urinary triclosan and serum thyroid function biomarker concentrations in women.Environment international · 2019Article
Corrections and comments
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Authors and funding
6 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Triclosan (TCS) and triclocarban (TCC) exposures are highly concerned due to their suspected endocrine-disrupting effects. The present study investigated TCS and TCC exposure levels in the general Chinese population by biomonitoring human urine and nail samples. TCS (69-80 %) and TCC (99-100 %) were frequently detected, which demonstrates that the general Chinese population has extensive exposure to these chemicals. The geometric mean (GM) urinary concentrations were 0.40 μg/g creatinine (creat), 95 % confidence interval (CI) 0.30-0.56, for TCS and 0.40 μg/g creat, 95 % CI 0.29-0.56, for TCC. On the other hand, the GM levels of TCS and TCC were 13.57 (5.67 μg/kg) and 84.66 μg/kg (41.50 μg/kg) in fingernail (toenail) samples, respectively, indicating that the levels in fingernails were approximately twice as high as those in toenails. Pearson's correlation coefficients between the urine and fingernail (toenail) samples were 0.715 (0.614) for TCS and 0.829 (0.812) for TCC. These data suggest that nail samples can be applied to the biomonitoring for TCS and TCC in the general population. We observed that the levels of both chemicals were higher in females than in males for urine and fingernail samples, but no significant differences were found between different genders for either compound in toenails. Nineteen- to 29-year-olds had the highest TCS levels in their nail samples, whereas TCC levels did not differ with regard to age. Region of residence significantly influenced TCS and TCC concentrations in the three biological matrices measured.
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