ArticlePharmacoEconomics2016
Calculating Total Health Service Utilisation and Costs from Routinely Collected Electronic Health Records Using the Example of Patients with Irritable Bowel Syndrome Before and After Their First Gastroenterology Appointment.
Article in PharmacoEconomics, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers, 1 of them a synthesis that pooled it.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
16 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Cost-of-Illness of Irritable Bowel Syndrome: A Systematic Review.Journal of gastroenterology and hepatology · 2026Pooled it
- Effects of treatment with eluxadoline on abdominal pain in patients with IBS-D: Additional post hoc analyses of Phase 3 trials.Neurogastroenterology and motility · 2020Trial
- The Cost of the Cure: Antibiotic Exposure as a Risk Factor for Irritable Bowel Syndrome.Antibiotics (Basel, Switzerland) · 2026Review
- Electroacupuncture Improving Intestinal Barrier Function in Rats with Irritable Bowel Syndrome Through Regulating Aquaporins.Digestive diseases and sciences · 2024Article
- A model to improve user acceptance of e-services in healthcare systems based on technology acceptance model: an empirical study.Journal of ambient intelligence and humanized computing · 2023Article
- Intensity of care in cancer patients in the last year of life: a retrospective data linkage study.British journal of cancer · 2022Article
- Direct healthcare costs of Rome IV or Rome III-defined irritable bowel syndrome in the United Kingdom.Alimentary pharmacology & therapeutics · 2022Article
- Mendelian randomization: estimation of inpatient hospital costs attributable to obesity.Health economics review · 2021Article
- The economic burden of infections following intramedullary nailing for a tibial shaft fracture in England.BMJ open · 2020Article
- Article
- Understanding symptom burden and attitudes to irritable bowel syndrome with diarrhoea: Results from patient and healthcare professional surveys.United European gastroenterology journal · 2018Article
- Integrating electronic healthcare records of armed forces personnel: Developing a framework for evaluating health outcomes in England, Scotland and Wales.International journal of medical informatics · 2018Article
- The global impact of IBS: time to think about IBS-specific models of care?Therapeutic advances in gastroenterology · 2017Review
- Self-help guidebook improved quality of life for patients with irritable bowel syndrome.PloS one · 2017Observational
- Complex temporal topic evolution modelling using the Kullback-Leibler divergence and the Bhattacharyya distance.EURASIP journal on bioinformatics & systems biology · 2016Article
- Big Data and Its Role in Health Economics and Outcomes Research: A Collection of Perspectives on Data Sources, Measurement, and Analysis.PharmacoEconomics · 2016Article
Corrections and comments
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Authors and funding
3 authors.
Funding
Abstract
introductionHealth economic models are increasingly important in funding decisions but most are based on data, which may therefore not represent the general population. We sought to establish the potential of real-world data available within the Clinical Practice Research Datalink (CPRD) and linked Hospital Episode Statistics (HES) to determine comprehensive healthcare utilisation and costs as input variables for economic modelling.
methodsA cohort of patients with irritable bowel syndrome (IBS) who first saw a gastroenterologist in 2008 or 2009, and with 3 years of data before and after their appointment, was created in the CPRD. Primary care, outpatient, inpatient, prescription and colonoscopy data were extracted from the linked CPRD and HES. The appropriate cost to the NHS was attached to each event. Total and stratified annual healthcare utilisation rates and costs were calculated before and after the gastroenterology appointment with distribution parameters. Absolute differences were calculated with 95% confidence intervals.
resultsTotal annual healthcare costs over 3 years increase by £935 (95% CI £928-941) following a gastroenterology appointment for IBS. We derived utilisation and cost data with parameter distributions stratified by demographics and time. Women, older patients, smokers and patients with greater comorbidity utilised more healthcare resources, which generated higher costs.
conclusionsThese linked datasets provide comprehensive primary and secondary care data for large numbers of patients, which allows stratification of outcomes. It is possible to derive input parameters appropriate for economic models and their distributions directly from the population of interest.
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