SynthesisParasites & vectors2015
Effect of gastro-intestinal nematode infection on sheep performance: a systematic review and meta-analysis.
Synthesis in Parasites & vectors, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 96 papers, 4 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
96 citing papers in PubMed, 4 syntheses or guidelines pooled it, 273 citations in OpenAlex.
- Multiscale epidemiology of gastrointestinal nematode infections in small ruminants: field evidence from Inner Mongolia and a national meta-analysis in China.BMC veterinary research · 2026Pooled it
- Anthelmintic resistance in livestock in Africa: review of the current status.BMC veterinary research · 2025Pooled it
- Immunoglobulins as Biomarkers for Gastrointestinal Nematodes Resistance in Small Ruminants: A systematic review.Scientific reports · 2020Pooled it
- Increasing importance of anthelmintic resistance in European livestock: creation and meta-analysis of an open database.Parasite (Paris, France) · 2020Pooled it
- Eprinomectin pour-on (EPRINEX® Pour-on, Merial): efficacy against gastrointestinal and pulmonary nematodes and pharmacokinetics in sheep.BMC veterinary research · 2017Trial
- Sheep Welfare in Confined and Pasture Production Systems: A Comparative Study with Emphasis on Parasitological Status.Veterinary sciences · 2026Article
- Molecular Epidemiology of Helminths at the Wildlife-Livestock Interface in Kazakhstan: Evidence from Sheep and Saiga.Pathogens (Basel, Switzerland) · 2026Article
- Climatic and Host-Related Drivers of Gastrointestinal Parasite Dynamics in Domestic Ruminants of North Bengal, India.Animals : an open access journal from MDPI · 2026Article
- Sheep Genetic Resistance to Gastrointestinal Nematode Infections: Current Insights from Transcriptomics and Other OMICs Technologies-A Review.Pathogens (Basel, Switzerland) · 2026Review
- Immunity to helminths in complex environments: co-infection disrupts effective granuloma formation and parasite clearance.Discovery immunology · 2026Article
- Modification of albendazole pharmacokinetics by menbutone administration in calves.Frontiers in veterinary science · 2026Article
- Infrared thermographic imaging as a promising on-farm method to estimate parasite load in dairy goats.Veterinary and animal science · 2025Article
- Study of coccidiosis dynamics in sheep in the northwest of Morocco.Open veterinary journal · 2025Article
- Chicory modulates the rumen environment in lambs with endoparasites.Scientific reports · 2025Article
- Application of Microbiome Feedback Theory to Animals: Can Parasites Drive Coexistence in Ungulate Communities?Integrative and comparative biology · 2025Article
- Safety and efficacy of a novel glycoengineered recombinant vaccine candidate against Haemonchus contortus in sheep.NPJ vaccines · 2025Article
- Disruptions in gene interaction networks abolish host susceptibility to Trichostrongylus colubriformis infections in sheep.PLoS neglected tropical diseases · 2025Article
- Comparing ShortAnimals : an open access journal from MDPI · 2025Article
- Inferring the energy cost of resistance to parasitic infection and its link to a trade-off.BMC ecology and evolution · 2025Article
- The anthelmintic activity of the white wormwood (Artemisia herba Alba) against Haemonchus contortus in beef cattle.Scientific reports · 2025Article
36 more citing papers are in PubMed but not listed here.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
3 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundGastrointestinal nematode (GIN) infections are common in domestic sheep and impact directly and indirectly on the health of infected animals as well as on the associated economic production. In this study, we aim at summarizing the current knowledge on the influence of GIN infections on sheep production by conducting a systematic review. A subsequent meta-analysis of relevant studies was performed to provide an estimate of the effect of GIN infections on weight gain, wool production and milk yield.
methodsA literature search was performed on the CAB, Pubmed and Web of Science database for the period 1960-2012. Inclusion criteria were: 1) Measurement of at least one production parameter. 2) Comparison between groups of sheep with different nematode burdens. 3) Same conditions regarding all aspects except parasite burden between groups. 4) Quantitative measurements of one or more production traits.
resultsAltogether, 88 studies describing 218 trials were included in this review. The majority of studies (86%) reported that GIN infections had a negative effect on production but this was reported to be statistically significant in only 43% of the studies. Meta-analysis indicated that performances of sheep infected with nematodes was 85, 90 and 78% of the performance in uninfected individuals for weight gain, wool production and milk yield respectively. Our results suggest a possible reporting bias or small study effect for the estimation of the impact of GIN infections on weight gain. Finally, a general linear model provided an estimate for the decrease in weight gain in relation to the increase in faecal egg count of nematodes.
conclusionThis study underlines the importance of GIN infections for sheep production and highlights the need to improve parasite management in sheep, in particular in face of challenges such as anthelmintic resistance.
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.