ArticleBMC plant biology2015
Analysis of genetic differentiation and genomic variation to reveal potential regions of importance during maize improvement.
Article in BMC plant biology, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers.
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17 citing papers in PubMed, 63 citations in OpenAlex.
- Decades' progress and prospects on maize functional genomics and molecular breeding.Science China. Life sciences · 2025Review
- Genetic Diversity and Construction of Salt-Tolerant Core Germplasm in Maize (Plants (Basel, Switzerland) · 2025Article
- Conservatively transmitted alleles of key agronomic genes provide insights into the genetic basis of founder parents in bread wheat (Triticum aestivum L.).BMC plant biology · 2023Article
- Integration of GWAS, linkage analysis and transcriptome analysis to reveal the genetic basis of flowering time-related traits in maize.Frontiers in plant science · 2023Article
- Analysis of Genetic Diversity and Population Structure of Cowpea (Plants (Basel, Switzerland) · 2022Article
- Genomic insights into historical improvement of heterotic groups during modern hybrid maize breeding.Nature plants · 2022Article
- Article
- Genome-wide association studies of leaf angle in maize.Molecular breeding : new strategies in plant improvement · 2021Article
- Genetic variation and population structure in China summer maize germplasm.Scientific reports · 2021Article
- Genetic diversity and population structure of early and extra-early maturing maize germplasm adapted to sub-Saharan Africa.BMC plant biology · 2021Article
- Population Structure and Genetic Diversity in Korean Cowpea Germplasm Based on SNP Markers.Plants (Basel, Switzerland) · 2020Article
- Genetic diversity among early provitamin A quality protein maize inbred lines and the performance of derived hybrids under contrasting nitrogen environments.BMC genetics · 2020Article
- Genetic architecture of phenotypic means and plasticities of kernel size and weight in maize.TAG. Theoretical and applied genetics. Theoretische und angewandte Genetik · 2019Article
- Genetic characterization of maize germplasm derived from Suwan population and temperate resources.Hereditas · 2019Article
- Genetic diversity and population structure of early-maturing tropical maize inbred lines using SNP markers.PloS one · 2019Article
- Characterizing the population structure and genetic diversity of maize breeding germplasm in Southwest China using genome-wide SNP markers.BMC genomics · 2016Article
- Exploring Identity-By-Descent Segments and Putative Functions Using Different Foundation Parents in Maize.PloS one · 2016Article
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9 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundExploring genetic differentiation and genomic variation is important for both the utilization of heterosis and the dissection of the genetic bases of complex traits.
methodsWe integrated 1857 diverse maize accessions from America, Africa, Europe and Asia to investigatetheir genetic differentiation, genomic variation using 43,252 high-quality single-nucleotide polymorphisms(SNPs),combing GWAS and linkage analysis strategy to exploring the function of relevant genetic segments.
resultsWe uncovered many more subpopulations that recently or historically formed during the breeding process. These patterns are represented by the following lines: Mo17, GB, E28, Ye8112, HZS, Shen137, PHG39, B73, 207, A634, Oh43, Reid Yellow Dent, and the Tropical/subtropical (TS) germplasm. A total of 85 highly differentiated regions with a DEST of more than 0.2 were identified between the TS and temperate subpopulations. These regions comprised 79% of the genetic variation, and most were significantly associated with adaptive traits. For example, the region containing the SNP tag PZE.108075114 was highly differentiated, and this region was significantly associated with flowering time (FT)-related traits, as supported by a genome-wide association study (GWAS) within the interval of FT-related quantitative trait loci (QTL). This region was also closely linked to zcn8 and vgt1, which were shown to be involved in maize adaptation. Most importantly, 197 highly differentiated regions between different subpopulation pairs were located within an FT- or plant architecture-related QTL.
conclusionsHere we reported that 700-1000 SNPs were necessary needed to robustly estimate the genetic differentiation of a naturally diverse panel. In addition, 13 subpopulations were observed in maize germplasm, 85 genetic regions with higher differentiation between TS and temperate maize germplasm, 197 highly differentiated regions between different subpopulation pairs, which contained some FT- related QTNs/QTLs/genes supported by GWAS and linkage analysis, and these regions were expected to play important roles in maize adaptation.
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