Evidence map›Paper›PMID 26496720›Full record

Trial reportBMC oral health2015

Early results of low-level laser application for masticatory muscle pain: a double-blind randomized clinical study.

Erkan Sancakli, Bilge Gökçen-Röhlıg, Ali Balık, Değer Öngül, Selin Kıpırdı, Haluk Keskın

Registry-linked trialOpen access · goldAbstract readRandomized Controlled Trial
PubMed Full text at PMC Publisher
In one paragraph

Trial report in BMC oral health, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT07125404 (Effectiveness of Low-Level Laser Auriculotherapy in the Treatment of Myogenic Temporomandibular Disorders and Anxiety), which is not on this map. Cited by 25 papers, 5 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
25citing papers in PubMed, 5 pooled it
4.9field-weighted citation impact, top 5% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT07125404 nanot yet recruitingnot on this mapstarted 2025, after this paper: background citation

Effectiveness of Low-Level Laser Auriculotherapy in the Treatment of Myogenic Temporomandibular Disorders and Anxiety: A Randomized Clinical Trial

TypeinterventionalSponsorQuiropraxia y EquilibrioRan2025 to 2026Enrolled32ConditionsTemporomandibular Disorder, Anxiety StateArmsLow-level laser auriculotherapy (LLLT-AT), Sham Low-level laser auriculotherapy (sham LLLT-AT), Myofascial release
3 · Its place in the literature

Who cites it

25 citing papers in PubMed, 5 syntheses or guidelines pooled it, 69 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 1 institution in 1 country.

Erkan SancakliDepartment of Prosthodontics, Faculty of Dentistry, Istanbul University, Capa, 34390, Istanbul, Turkey. esancak@istanbul.edu.tr.
Bilge Gökçen-RöhlıgDepartment of Prosthodontics, Faculty of Dentistry, Istanbul University, Capa, 34390, Istanbul, Turkey.
Ali BalıkDepartment of Prosthodontics, Faculty of Dentistry, Istanbul University, Capa, 34390, Istanbul, Turkey.
Değer ÖngülDepartment of Prosthodontics, Faculty of Dentistry, Istanbul University, Capa, 34390, Istanbul, Turkey.
Selin KıpırdıDepartment of Prosthodontics, Faculty of Dentistry, Istanbul University, Capa, 34390, Istanbul, Turkey.
Haluk KeskınDepartment of Prosthodontics, Faculty of Dentistry, Istanbul University, Capa, 34390, Istanbul, Turkey.
Istanbul University · TR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundTo evaluate the effect of Low Level Laser (LLL) application at the points of greatest pain in patients with chronic masticatory muscle pain.

methodsA total number of 30 (21 women, 9 men, with a mean age of 39.2) were selected after the diagnosis of MPDS according to the Research Diagnostic Criteria for Temporomandibular Disorder (RDC/TMD). The patients were randomly divided into three groups; laser group I (n = 10); patients received the LLL at the point of greatest pain, laser group II (n = 10); patients received LLL at pre-established points in the effected muscles and placebo group (n = 10). LLL and placebo were applied three times per week, for a total of 12 sessions. Mandibular mobility was examined, masticator muscles tenderness were assessed and PPT values were obtained. Subjective pain levels were evaluated using VAS. The measurements performed before the treatment and after the completion of the therapy. Descriptive statistics (mean, standard deviation, and frequency) Student's t-test, Mann-Whitney U-test and paired-sample t-tests were used for analysis.

resultsIn both laser groups, there was a statically significant reduction in PPT values of the muscles, number of muscles without any pain on palpation increased significantly, mandibular movements' ranges were improved. Laser group I demonstrated statistically better results than the Laser group II in all of the measured values. Plasebo group did not show any statistically difference in any of the measured values.

conclusionsLLLT can be accepted as an alternative treatment modality in the management of masticatory muscle pain and direct irradiation seems to effect better.

trial registrationCurrent Controlled Trials ISRCTN31085 , Date of registration 28/08/20145.

Indexed as

Laser TherapyMasticatory MusclesPain ManagementAdultDouble-Blind MethodFemaleHumansMaleTemporomandibular Joint Disorders

Identifiers

PMID26496720
PMCPMC4619518
OpenAlexW2147280776

What OpenQuestion holds

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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.