Evidence map›Paper›PMID 26496597›Full record

ArticleCell2015

Bacterial backstabbing: EF-Tu, brute?

Matthew T Cabeen, Richard Losick

Abstract readComment
PubMed Publisher
In one paragraph

Article in Cell, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

2 authors.

Matthew T CabeenDepartment of Molecular and Cellular Biology, Harvard University, Cambridge, MA 02138, USA.
Richard LosickDepartment of Molecular and Cellular Biology, Harvard University, Cambridge, MA 02138, USA. Electronic address: losick@mcb.harvard.edu.

Funding

Training in Molecular, Cellular, and Chemical BiologyT32GM007598 · NIGMS · HARVARD UNIVERSITY · PI DULAC, CATHERINE · 1985 to 2019
$16.2M
Role of RNA Polymerase in Bacterial DifferentionR01GM018568 · NIGMS · HARVARD UNIVERSITY · PI LOSICK, RICHARD MARC · 1985 to 2018
$11.5M
NIGMS NIH HHS R01 GM018568NIGMS NIH HHS T32 GM007598
6 · The paper itself

Abstract

Bacterial type VI secretion is an offensive and defensive weapon that utilizes a molecular warhead to inject toxins into neighboring cells. In this issue of Cell, Whitney et al. report a new class of toxin that disrupts the core metabolism of recipient cells and uncover a surprising requirement for EF-Tu.

Indexed as

Bacterial ToxinsNAD+ NucleosidasePeptide Elongation Factor TuPseudomonas aeruginosaType VI Secretion SystemsBacterial ToxinsNAD+ NucleosidasePeptide Elongation Factor TuType VI Secretion Systems

Identifiers

PMID26496597

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.