Evidence map›Paper›PMID 26496331›Full record

Trial reportMedicine2015

Oscillating Positive Expiratory Pressure on Respiratory Resistance in Chronic Obstructive Pulmonary Disease With a Small Amount of Secretion: A Randomized Clinical Trial.

Ada Clarice Gastaldi, Paolo Paredi, Anjana Talwar, Sally Meah, Peter J Barnes, Omar S Usmani

2 registry-linked trialsOpen access · goldAbstract readRandomized Controlled Trial
In one paragraph

Trial report in Medicine, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to 2 registered trials, which are not on this map. Cited by 11 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed, 1 pooled it
1.0field-weighted citation impact, top 21% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT01832961 nacompletednot on this map

Acute Effects of a Flutter Device on Airways Resistance in Chronic Obstructive Pulmonary Disease (COPD)

TypeinterventionalSponsorImperial College LondonRan2013 to 2013Enrolled15ConditionsChronic Obstructive Pulmonary DiseaseArmsFlutter valve exercises, Flutter Sham exercises, Flutter and bronchodilator exercises
NCT05491876 nacompletednot on this mapstarted 2021, after this paper: background citation

Comparison Of Active Cycle Of Breathing Technique And Breathing Exercises On Oxygen Saturation And Pulmonary Function Test In Post ICU COVID-19 Patients

TypeinterventionalSponsorRiphah International UniversityRan2021 to 2022Enrolled48ConditionsPost Covid-19 PatientsArmsChest physiotherapy with breathing exercises and ACBT, Chest physiotherapy with breathing exercises
3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 1 synthesis or guideline pooled it, 20 citations in OpenAlex.

  1. Pooled it
  2. Trial
  3. Trial
  4. Article
  5. Impact of AerobikaFrontiers in medicine · 2023
    Article
  6. Article
  7. Article
  8. Article
  9. Exercise and Cystic Fibrosis.Advances in experimental medicine and biology · 2020
    Review
  10. Article
  11. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 1 institution in 1 country.

Ada Clarice GastaldiFrom the Physiotherapy Course, School of Medicine of Ribeirão Preto, São Paulo University, Brazil (ACG); Airway Disease Section, National Heart and Lung Institute, Imperial College London& Royal Brompton Hospital, United Kingdom (PP, SM, PJB, OSU); and Department of Physiology, All India Institute of Medical Sciences, India (AT).
Paolo Paredi
Anjana Talwar
Sally Meah
Peter J Barnes
Omar S Usmani
American College of Gastroenterology · US

Funding

Department of Health CDF-2011-04-053
6 · The paper itself

Abstract

This study aims to evaluate the acute effects of an oscillating positive expiratory pressure device (flutter) on airways resistance in patients with chronic obstructive pulmonary disease (COPD).Randomized crossover study: 15 COPD outpatients from Asthma Lab-Royal Brompton Hospital underwent spirometry, impulse oscillometry (IOS) for respiratory resistance (R) and reactance (X), and fraction exhaled nitric oxide (FeNO) measures.Thirty minutes of flutter exercises: a "flutter-sham" procedure was used as a control, and airway responses after a short-acting bronchodilator were also assessed.Respiratory system resistance (R): in COPD patients an increase in X5insp (-0.21 to -0.33 kPa/L/s) and Fres (24.95 to 26.16 Hz) occurred immediately after flutter exercises without bronchodilator. Following 20 min of rest, a decrease in the R5, ΔR5, R20, X5, and Ax was observed, with R5, R20, and X5 values lower than baseline, with a moderate effect size; there were no changes in FeNO levels or spirometry.The use of flutter can decrease the respiratory system resistance and reactance and expiratory flow limitation in stable COPD patients with small amounts of secretions.

Indexed as

Exercise TherapyAgedCross-Over StudiesHumansPositive-Pressure RespirationPulmonary Disease, Chronic ObstructiveSputum

Identifiers

PMID26496331
PMCPMC4620777
OpenAlexW2317219482

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.