Evidence map›Paper›PMID 26495405›Full record

ArticleEmergency (Tehran, Iran)2015

The Effect of Blood Loss in the Presence and Absence of Severe Soft Tissue Injury on Hemodynamic and Metabolic Parameters; an Experimental study.

Ali Mohammad Moradi, Omid Aj, Shahram Paydar, Farzaneh Ketabchi, Seyed Mostafa Sheid Moosavi, Shahram Bolandparvaz, Hamid Reza Abassi, Aryan Dokht Tamadon, Davood Mehrabani

Open access · greenAbstract read
PubMed Full text at PMC
In one paragraph

Article in Emergency (Tehran, Iran), 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact, top 91% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed, 0 citations in OpenAlex.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 2 institutions in 1 country.

Ali Mohammad MoradiDepartment of Surgery, Trauma Research Center, Shiraz University of Medical Sciences, Shiraz, Iran.
Omid AjDepartment of Surgery, Trauma Research Center, Shiraz University of Medical Sciences, Shiraz, Iran.
Shahram PaydarDepartment of Surgery, Trauma Research Center, Shiraz University of Medical Sciences, Shiraz, Iran.
Farzaneh KetabchiDepartment of Physiology, School of Medicine, Shiraz University of Medical Sciences, Shiraz, Iran.
Seyed Mostafa Sheid MoosaviDepartment of Physiology, School of Medicine, Shiraz University of Medical Sciences, Shiraz, Iran.
Shahram BolandparvazDepartment of Surgery, Trauma Research Center, Shiraz University of Medical Sciences, Shiraz, Iran.
Hamid Reza AbassiDepartment of Surgery, Trauma Research Center, Shiraz University of Medical Sciences, Shiraz, Iran.
Aryan Dokht TamadonStem Cell and Transgenic Technology Research Center, Shiraz University of Medical Sciences, Shiraz, Iran.
Davood MehrabaniStem Cell and Transgenic Technology Research Center, Shiraz University of Medical Sciences, Shiraz, Iran.
Shiraz University of Medical Sciences · IRStem Cell Technology Research Center · IR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

introductionThe effect of severe soft tissue injury on the severity of hemorrhagic shock is still unknown. Therefore, the present study was aimed to determine hemodynamic and metabolic changes in traumatic/hemorrhagic shock in an animal model.

methodsForty male rats were randomly divided into 4 equal groups including sham, hemorrhagic shock, soft tissue injury, and hemorrhagic shock + soft tissue injury groups. The changes in blood pressure, central venous pressure (CVP) level, acidity (pH), and base excess were dynamically monitored and comparedsented.

resultsMean arterial blood pressure decreased significantly in hemorrhagic shock (df: 12; F=10.9; p<0.001) and severe soft tissue injury + hemorrhagic shock (df: 12; F=11.7; p<0.001) groups 15 minutes and 5 minutes after injury, respectively. A similar trend was observed in CVP in severe soft tissue injury + hemorrhagic shock group (df: 12; F=8.9; p<0.001). After 40 minutes, pH was significantly lower in hemorrhagic shock (df: 12; F=6.8; p=0.009) and severe soft tissue injury + hemorrhagic shock (df: 12; F=7.9; p=0.003) groups. Base excess changes during follow ups have a similar trend. (df: 12; F=11.3; p<0.001).

conclusionThe results of this study have shown that the effect of hemorrhage on the decrease of mean arterial blood pressure, CVP, pH, and base excess is the same in the presence or absence of soft tissue injury.

Indexed as

hemodynamicshemorrhagicShocksoft tissue injuries

Identifiers

PMID26495405
PMCPMC4608348
OpenAlexW2169804923

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.