ReviewJournal of immunology research2015
Comparative Immune Response in Children and Adults with H. pylori Infection.
Review in Journal of immunology research, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 33 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
33 citing papers in PubMed, 64 citations in OpenAlex.
- Helicobacter pylori infection among the Dayak community in Kuching Division, Sarawak: findings from a community-based study.BMC gastroenterology · 2026Article
- Pathogenicity and virulence ofVirulence · 2025Review
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- Vitiligo: are microbes to blame?Bioscience of microbiota, food and health · 2025Review
- Developing a potent vaccine againstExpert reviews in molecular medicine · 2024Review
- Mucosal Immunity Related to CD8Pediatric gastroenterology, hepatology & nutrition · 2024Article
- Establishment of novel immortalized middle ear cell lines as models for otitis media.Laryngoscope investigative otolaryngology · 2023Article
- Review
- The Influence ofAntibiotics (Basel, Switzerland) · 2023Review
- Inflammatory microenvironment in gastric premalignant lesions: implication and application.Frontiers in immunology · 2023Review
- Review
- IFNγ-dependent silencing of TFF1 duringOpen biology · 2022Article
- Old and New Aspects ofChildren (Basel, Switzerland) · 2022Review
- FromWorld journal of clinical oncology · 2022Review
- Article
- DifferentialFrontiers in immunology · 2022Article
- Review
- How did the ancient bacterium,JGH open : an open access journal of gastroenterology and hepatology · 2021Article
- Acceptive Immunity: The Role of Fucosylated Glycans in Human Host-Microbiome Interactions.International journal of molecular sciences · 2021Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
7 authors at 3 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Helicobacter pylori (H. pylori) infection is generally acquired during early childhood; therefore, the immune response which usually takes place at this age may influence or even determine susceptibility to the infection contributing to the clinical outcomes in adulthood. Several cytokines including IL-6, IL-10, and TGF-β1 as well as Foxp3(+) cell numbers have been shown to be higher; however, some other cytokines consisting of IL-1β, IL-17A, and IL-23 are lower in infected children than in infected adults. Immune response to H. pylori infection in children is predominant Treg instead of Th17 cell response. These results indicate that immune system responses probably play a role in persistent H. pylori infection. Childhood H. pylori infection is also associated with significantly lower levels of inflammation and ulceration compared with adults. This review, therefore, aimed to provide critical findings of the available literature about comparative immune system in children and adults with H. pylori infection.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.