Evidence map›Paper›PMID 26495294›Full record

ArticleBioMed research international2015

Breast cancer by age at diagnosis in the Gharbiah, Egypt, population-based registry compared to the United States Surveillance, Epidemiology, and End Results Program, 2004-2008.

Jennifer A Schlichting, Amr S Soliman, Catherine Schairer, Joe B Harford, Ahmed Hablas, Mohamed Ramadan, Ibrahim Seifeldin, Sofia D Merajver

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in BioMed research international, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
17citing papers in PubMed, 2 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

17 citing papers in PubMed, 2 syntheses or guidelines pooled it.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Jennifer A SchlichtingDepartment of Epidemiology, University of Michigan School of Public Health, Ann Arbor, MI 48109, USA.
Amr S SolimanDepartment of Epidemiology, University of Nebraska Medical Center, Omaha, NE 68198, USA.
Catherine SchairerDivision of Cancer Epidemiology and Genetics, National Cancer Institute, National Institutes of Health, Department of Health and Human Services, Bethesda, MD 20892, USA.
Joe B HarfordCenter for Global Health, National Cancer Institute, National Institutes of Health, Department of Health and Human Services, Bethesda, MD 20892, USA.
Ahmed HablasTanta Cancer Center, Tanta, Gharbiah 31111, Egypt.
Mohamed RamadanTanta Cancer Center, Tanta, Gharbiah 31111, Egypt.
Ibrahim SeifeldinTanta Cancer Center, Tanta, Gharbiah 31111, Egypt.
Sofia D MerajverDepartment of Epidemiology, University of Michigan School of Public Health, Ann Arbor, MI 48109, USA ; Department of Internal Medicine, University of Michigan Medical School, Ann Arbor, MI 48109, USA.

Funding

Cancer Epidemiology Education in Special Populations Program-15R25CA112383 · NCI · UNIVERSITY OF NEBRASKA MEDICAL CENTER · PI Amr Soliman · 2006 to 2026
$6.1M
NCI NIH HHS R25 CA112383NCI NIH HHS R25CA112383
6 · The paper itself

Abstract

objectiveAlthough breast cancers (BCs) in young women often display more aggressive features, younger women are generally not screened for early detection. It is important to understand the characteristics of young onset breast cancer to increase awareness in this population. This analysis includes all ages, with emphasis placed on younger onset BC in Egypt as compared to the United States.

methodsBC cases in the Gharbiah cancer registry (GCR), Egypt, were compared to those in the Surveillance, Epidemiology, and End Results (SEER) database. This analysis included 3,819 cases from the GCR and 273,019 from SEER diagnosed 2004-2008.

resultsGCR cases were diagnosed at later stages, with <5% diagnosed at Stage I and 12% diagnosed at Stage IV. 48% of all SEER cases were diagnosed at Stage I, dropping to 30% among those ≤40. Significant differences in age, tumor grade, hormone receptor status, histology, and stage exist between GCR and SEER BCs. After adjustment, GCR cases were nearly 45 times more likely to be diagnosed at stage III and 16 times more likely to be diagnosed at stage IV than SEER cases.

conclusionsFuture research should examine ways to increase literacy about early detection and prompt therapy in young cases.

Indexed as

RegistriesAdultAgedAged, 80 and overAge DistributionBreast NeoplasmsEarly Detection of CancerEgyptFemaleHumansIncidenceMiddle AgedPopulation SurveillanceReproducibility of ResultsRisk FactorsSensitivity and Specificity

Identifiers

PMID26495294
PMCPMC4606134

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.