ArticleIranian journal of pediatrics2015
Atopic Manifestations: Dermatitis, Allergic Rhinitis and Asthma in Patients With Hypogammaglobulinemia.
Article in Iranian journal of pediatrics, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.
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Who cites it
5 citing papers in PubMed, 10 citations in OpenAlex.
- Hypogammaglobulinemia in Children with Atopic Dermatitis.Children (Basel, Switzerland) · 2026Article
- The prevalence of allergic manifestations in inborn errors of immunity: a retrospective cohort study.BMC immunology · 2025Article
- Organ-based clues for diagnosis of inborn errors of immunity: A practical guide for clinicians.Immunity, inflammation and disease · 2023Review
- Serum Allergen-Specific IgE among Pediatric Patients with Primary Immunodeficiency.Children (Basel, Switzerland) · 2022Article
- The Epidemiology and Clinical Presentations of Atopic Diseases in Selective IgA Deficiency.Journal of clinical medicine · 2021Review
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Authors and funding
4 authors at 2 institutions in 1 country.
Funding
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Abstract
backgroundMost of the hypogammaglobulinemic patients have a clinical history in favor of allergic respiratory disease. Nevertheless, in these patients the importance and prevalence of atopic disorders have not been completely explained.
objectivesThis study was aimed to evaluate atopic manifestations (dermatitis, allergic rhinitis and asthma) and pulmonary function in patients with hypogammaglobulinemia. PATIENTS AND
methodsWe used the international study of asthma and allergies in childhood (ISAAC) questionnaire in forty-five patients diagnosed with hypogammaglobulinemia and spirometry was done in 41 patients older than 5 years.
resultsSpirometry results were normal in 21 (51%), and showed obstructive in 15 (37%) and restrictive pattern in 5 (12%) of the 41 patients who were evaluated. By the end of the study, asthma was diagnosed in nine (20%) patients and other atopies (rhinitis and dermatitis) identified in 10 (22%), and four (9%), respectively.
conclusionsAtopic conditions should be investigated in the hypogammaglobulinemic patients and the prevalence in these patients may be higher than in normal population. Also, it is recommended to perform a pulmonary function test as a routine procedure in patients with hypogammaglobulinemia and atopy should be assessed in these patients.
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