Evidence map›Paper›PMID 26494953›Full record

ReviewWorld journal of gastroenterology2015

Companion diagnostics for the targeted therapy of gastric cancer.

Changhoon Yoo, Young Soo Park

Abstract readReview
In one paragraph

Review in World journal of gastroenterology, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed.

  1. Review
  2. Antibody-drug conjugates in gastric cancer: from molecular landscape to clinical strategies.Gastric cancer : official journal of the International Gastric Cancer Association and the Japanese Gastric Cancer Association · 2024
    Review
  3. Article
  4. Review
  5. Article
  6. Article
  7. Article
  8. Article
  9. Article
  10. Prognostic Value of Upregulation of Myristoylated Alanine-Rich C-Kinase Substrate in Gastric Cancer.Medical science monitor : international medical journal of experimental and clinical research · 2019
    Article
  11. Novel genomic prognostic biomarkers for dogs with cancer.Journal of veterinary internal medicine
    Article
  12. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

Changhoon YooChanghoon Yoo, Departments of Oncology, Asan Medical Center, University of Ulsan College of Medicine, Seoul 138-736, South Korea.
Young Soo ParkChanghoon Yoo, Departments of Oncology, Asan Medical Center, University of Ulsan College of Medicine, Seoul 138-736, South Korea.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Gastric cancer is the fourth most common type of cancer and represents a major cause of cancer-related deaths worldwide. With recent biomedical advances in our understanding of the molecular characteristics of gastric cancer, many genetic alterations have been identified as potential targets for its treatment. Multiple novel agents are currently under development as the demand for active agents that improve the survival of gastric cancer patients constantly increases. Based on lessons from previous trials of targeted agents, it is now widely accepted that the establishment of an optimal diagnostic test to select molecularly defined patients is of equal importance to the development of active agents against targetable genetic alterations. Herein, we highlight the current status and future perspectives of companion diagnostics in the treatment of gastric cancer.

Indexed as

Molecular Diagnostic TechniquesMolecular Targeted TherapyPrecision MedicineAnimalsAntineoplastic AgentsBiomarkers, TumorHumansPatient SelectionPredictive Value of TestsPrognosisSignal TransductionStomach NeoplasmsAntineoplastic AgentsBiomarkers, TumorCompanion diagnosticsFibroblast growth factor receptorGastric cancerHepatocyte growth factor receptorHuman epidermal growth factor receptor 2

Identifiers

PMID26494953
PMCPMC4607896

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.