Evidence map›Paper›PMID 26494421›Full record

ArticleBMC musculoskeletal disorders2015

Development and feasibility of a personalized, interactive risk calculator for knee osteoarthritis.

Elena Losina, Kristina Klara, Griffin L Michl, Jamie E Collins, Jeffrey N Katz

Registry-linked trialOpen access · goldAbstract read
In one paragraph

Article in BMC musculoskeletal disorders, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT02704286 (Raising Awareness of Knee Osteoarthritis), which is not on this map. Cited by 17 papers.

0numbers the graph read from it
0cells of the map it votes in
17citing papers in PubMed
1.9field-weighted citation impact, top 15% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT02704286 nacompletednot on this map

Raising Awareness of Knee Osteoarthritis (OA) and Willingness to Undertake Behavioral Changes to Reduce Risk of Knee OA: Online Recruitment

TypeinterventionalSponsorBrigham and Women's HospitalRan2015 to 2015Enrolled380ConditionsKnee OsteoarthritisArmsInternet-Based Osteoarthritis Risk Calculator, Generic osteoarthritis information
3 · Its place in the literature

Who cites it

17 citing papers in PubMed, 41 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 1 institution in 1 country.

Elena LosinaOrthopaedic and Arthritis Center for Outcomes Research, Department of Orthopedic Surgery, Brigham and Women's Hospital, 75 Francis St, BC 4-016, 02115, Boston, MA, USA. elosina@partners.org.
Kristina KlaraOrthopaedic and Arthritis Center for Outcomes Research, Department of Orthopedic Surgery, Brigham and Women's Hospital, 75 Francis St, BC 4-016, 02115, Boston, MA, USA. kristina.klara@gmail.com.
Griffin L MichlOrthopaedic and Arthritis Center for Outcomes Research, Department of Orthopedic Surgery, Brigham and Women's Hospital, 75 Francis St, BC 4-016, 02115, Boston, MA, USA. griffinmichl@gmail.com.
Jamie E CollinsOrthopaedic and Arthritis Center for Outcomes Research, Department of Orthopedic Surgery, Brigham and Women's Hospital, 75 Francis St, BC 4-016, 02115, Boston, MA, USA. jcollins13@partners.org.
Jeffrey N KatzOrthopaedic and Arthritis Center for Outcomes Research, Department of Orthopedic Surgery, Brigham and Women's Hospital, 75 Francis St, BC 4-016, 02115, Boston, MA, USA. jnkatz@partners.org.
Brigham and Women's Hospital · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundThe incidence of knee osteoarthritis (OA) is rising. While several risk factors have been associated with the development of knee OA, this information is not readily accessible to those at risk for osteoarthritis. Risk calculators have been developed for several prevalent chronic conditions but not for OA. Using published evidence on established risk factors, we developed an interactive, personalized knee OA risk calculator (OA Risk C) and conducted a pilot study to evaluate its acceptability and feasibility.

methodsWe used the Osteoarthritis Policy (OAPol) Model, a validated, state-transition simulation of the natural history and management of OA, to generate data for OA Risk C. Risk estimates for calculator users were based on a set of demographic and clinical factors (age, sex, race/ethnicity, obesity) and select risk factors (family history of knee OA, occupational exposure, and history of knee injury). OA Risk C presents personalized risk of knee OA in several ways to maximize understanding among a wide range of users. We conducted a study of 45 subjects in a primary care setting to establish the feasibility and acceptability of the OA risk calculator. Pilot study participants were asked several questions regarding ease of use, clarity of presentation, and clarity of the graphical representation of their risk. These questions used a five-level agreement scale ranging from strongly disagree to strongly agree.

resultsOA Risk C depicts information about users' risk of symptomatic knee OA in 5 year intervals. Study participants estimated their lifetime risk at 38 %, while their actual lifetime risk, as estimated by OA Risk C, was 25 %. Eighty-four percent of pilot study participants reported that OA Risk C was easy to understand, and 89 % agreed that the graphs depicting their risk were clear and comprehensible.

conclusionsWe have developed a personalized, computer-based OA risk calculator that is easy to use. OA Risk C may be utilized to estimate individuals' knee OA risk and to deliver educational and behavioral interventions focused on osteoarthritis risk reduction.

Indexed as

Osteoarthritis, KneePrimary Health CareAdultFeasibility StudiesFemaleHumansMaleMiddle AgedPilot ProjectsRisk Assessment

Identifiers

PMID26494421
PMCPMC4618755
OpenAlexW2140012387

What OpenQuestion holds

Textmetadata
LicenceCC BY
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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.