ArticleScientific reports2015
Toxicological and biochemical analyses demonstrate no toxic effect of Cry1C and Cry2A to Folsomia candida.
Article in Scientific reports, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers, 1 of them a synthesis that pooled it.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
14 citing papers in PubMed, 1 synthesis or guideline pooled it, 37 citations in OpenAlex.
- The effect of Bt crops on soil invertebrates: a systematic review and quantitative meta-analysis.Transgenic research · 2020Pooled it
- An environmental risk assessment of maize containing event, DP-Ø51291-2, with activity against corn rootworms (GM crops & food · 2025Article
- Neutral Dietary Effects of Two MicroRNAs, Csu-Novel-260 and Csu-Mir-14, on the Non-Target ArthropodPlants (Basel, Switzerland) · 2023Article
- Impact of TransgenicPlants (Basel, Switzerland) · 2022Article
- Climate change did not alter the effects of Bt maize on soil Collembola in northeast China.Scientific reports · 2022Article
- Biochemical analyses demonstrate that Bt maize has no adverse effects on Eisenia fetida.PloS one · 2022Article
- Efficient Transformation ofFrontiers in plant science · 2021Article
- Toxicological and biochemical analyses demonstrate no toxic effect of Bt maize on the Folsomia candida.PloS one · 2020Article
- Article
- Toxicological and Biochemical Analyses Demonstrate the Absence of Lethal or Sublethal Effects ofFrontiers in plant science · 2018Article
- Article
- The tiered-evaluation of the effects of transgenic cry1c rice on Cyrtorhinus lividipennis, a main predator of Nilaparvata lugens.Scientific reports · 2017Article
- Quality of laboratory studies assessing effects of Bt-proteins on non-target organisms: minimal criteria for acceptability.Transgenic research · 2016Review
- Assessment of Potential Risks of Dietary RNAi to a Soil Micro-arthropod, Sinella curviseta Brook (Collembola: Entomobryidae).Frontiers in plant science · 2016Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
7 authors at 4 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Collembolans are common soil arthropods that may be exposed to insecticidal proteins produced in genetically engineered (GE) plants by ingestion of crop residues or root exudates. In the present study, a dietary exposure assay was validated and used to assess the lethal and sublethal effects of two Bacillus thuringiensis (Bt) insecticidal proteins, Cry1C and Cry2A, on Folsomia candida. Using the insecticidal compounds potassium arsenate (PA), protease inhibitor (E-64), and Galanthus nivalis agglutinin (GNA) mixed into Baker's yeast, we show that the assay used can detect adverse effects on F. candida. Survival and development were significantly reduced when F. candida was fed a diet containing PA, E-64, and GNA at 9, 75, and 100 μg/g diet, respectively, but not when fed a diet containing 300 μg/g Cry1C or 600 μg/g Cry2A. The activities of test antioxidant-, detoxification-, and digestion-related enzymes in F. candida were unaltered by a diet containing 300 μg/g Cry1C or 600 μg/g Cry2A, but were significantly increased by a diet containing 75 μg/g E-64. The results confirm that Cry1C and Cry2A are not toxic to F. candida at concentrations that are much higher than those encountered under field conditions.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.