Evidence map›Paper›PMID 26493801›Full record

ArticleThe European respiratory journal2015

Lung function in children in relation to ethnicity, physique and socioeconomic factors.

Sooky Lum, Vassiliki Bountziouka, Samatha Sonnappa, Angie Wade, Tim J Cole, Seeromanie Harding, Jonathan C K Wells, Chris Griffiths, Philip Treleaven, Rachel Bonner and 8 more

Abstract read
In one paragraph

Article in The European respiratory journal, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 26 papers, 3 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
26citing papers in PubMed, 3 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

26 citing papers in PubMed, 3 syntheses or guidelines pooled it.

  1. Guideline
  2. Pooled it
  3. Pooled it
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  7. Review
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  9. Article
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  14. Article
  15. Is There a Role for Using Race-Specific Reference Equations? Yes and No.American journal of respiratory and critical care medicine · 2022
    Article
  16. Reconsidering the Utility of Race-Specific Lung Function Prediction Equations.American journal of respiratory and critical care medicine · 2022
    Observational
  17. Review
  18. Article
  19. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

18 authors.

Sooky LumRespiratory, Critical Care & Anaesthesia Section in IIIP Programme, UCL Institute of Child Health, London, UK s.lum@ucl.ac.uk.
Vassiliki BountzioukaRespiratory, Critical Care & Anaesthesia Section in IIIP Programme, UCL Institute of Child Health, London, UK.
Samatha SonnappaRespiratory, Critical Care & Anaesthesia Section in IIIP Programme, UCL Institute of Child Health, London, UK UCL Institute of Global Health, London, UK.
Angie WadePopulation, Policy and Practice Programme, UCL Institute of Child Health, London, UK.
Tim J ColePopulation, Policy and Practice Programme, UCL Institute of Child Health, London, UK.
Seeromanie HardingMRC Social and Public Health Sciences Unit, University of Glasgow, Glasgow, UK.
Jonathan C K WellsPopulation, Policy and Practice Programme, UCL Institute of Child Health, London, UK.
Chris GriffithsAsthma UK Centre for Applied Research, Blizard Institute - Queen Mary University of London, London, UK.
Philip TreleavenDept of Computer Science, UCL, London, UK.
Rachel BonnerRespiratory, Critical Care & Anaesthesia Section in IIIP Programme, UCL Institute of Child Health, London, UK.
Jane KirkbyRespiratory, Critical Care & Anaesthesia Section in IIIP Programme, UCL Institute of Child Health, London, UK Great Ormond Street Hospital for Children NHS Foundation Trust, London, UK.
Simon LeeRespiratory, Critical Care & Anaesthesia Section in IIIP Programme, UCL Institute of Child Health, London, UK.
Emma RaywoodRespiratory, Critical Care & Anaesthesia Section in IIIP Programme, UCL Institute of Child Health, London, UK.
Sarah LeggRespiratory, Critical Care & Anaesthesia Section in IIIP Programme, UCL Institute of Child Health, London, UK.
Dave SearsRespiratory, Critical Care & Anaesthesia Section in IIIP Programme, UCL Institute of Child Health, London, UK.
Philippa CottamRespiratory, Critical Care & Anaesthesia Section in IIIP Programme, UCL Institute of Child Health, London, UK.
Colin FeyerabandABS Laboratories, Welwyn Garden City, UK.
Janet StocksRespiratory, Critical Care & Anaesthesia Section in IIIP Programme, UCL Institute of Child Health, London, UK.

Funding

Medical Research Council MC_EX_G0701943Medical Research Council MC_U130015185Medical Research Council MC_UU_12017/1Medical Research Council MR/J004839/1Medical Research Council MR/M012069/1Wellcome Trust 094129Wellcome Trust WT094129MA
6 · The paper itself

Abstract

Can ethnic differences in spirometry be attributed to differences in physique and socioeconomic factors?Assessments were undertaken in 2171 London primary schoolchildren on two occasions 1 year apart, whenever possible, as part of the Size and Lung function In Children (SLIC) study. Measurements included spirometry, detailed anthropometry, three-dimensional photonic scanning for regional body shape, body composition, information on ethnic ancestry, birth and respiratory history, socioeconomic circumstances, and tobacco smoke exposure.Technically acceptable spirometry was obtained from 1901 children (mean (range) age 8.3 (5.2-11.8) years, 46% boys, 35% White, 29% Black-African origin, 24% South-Asian, 12% Other/mixed) on 2767 test occasions. After adjusting for sex, age and height, forced expiratory volume in 1 s was 1.32, 0.89 and 0.51 z-score units lower in Black-African origin, South-Asian and Other/mixed ethnicity children, respectively, when compared with White children, with similar decrements for forced vital capacity (p<0.001 for all). Although further adjustment for sitting height and chest width reduced differences attributable to ethnicity by up to 16%, significant differences persisted after adjusting for all potential determinants, including socioeconomic circumstances.Ethnic differences in spirometric lung function persist despite adjusting for a wide range of potential determinants, including body physique and socioeconomic circumstances, emphasising the need to use ethnic-specific equations when interpreting results.

Indexed as

Body SizeEthnicitySocioeconomic FactorsAsian PeopleBlack PeopleBody HeightChildChild, PreschoolFemaleForced Expiratory VolumeHumansLondonLungMaleOrgan SizeSex FactorsTobacco Smoke Pollution

Identifiers

PMID26493801
PMCPMC4668600

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.