Evidence map›Paper›PMID 26493309›Full record

ArticleEuropean journal of nuclear medicine and molecular imaging2016

Endogenous TSH levels at the time of

Alexis Vrachimis, Burkhard Riemann, Uwe Mäder, Christoph Reiners, Frederik A Verburg

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Article in European journal of nuclear medicine and molecular imaging, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
19citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

19 citing papers in PubMed, 1 synthesis or guideline pooled it.

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  15. Evaluation ofEuropean journal of nuclear medicine and molecular imaging · 2017
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Alexis VrachimisDepartment of Nuclear Medicine, University Hospital Münster, Münster, Germany.
Burkhard RiemannDepartment of Nuclear Medicine, University Hospital Münster, Münster, Germany.
Uwe MäderDepartment of Nuclear Medicine, University of Würzburg, Würzburg, Germany.
Christoph ReinersDepartment of Nuclear Medicine, University of Würzburg, Würzburg, Germany.
Frederik A VerburgDepartment of Nuclear Medicine, University of Würzburg, Würzburg, Germany. fverburg@ukaachen.de.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeBased on a single older study it is established dogma that TSH levels should be ≥30 mU/l at the time of postoperative

methodsA total of 1,873 patients without distant metastases referred for postoperative adjuvant

resultsAge, gender and the presence of lymph node metastases were independent determinants of TSH levels at the time of ablation. TSH levels were not significantly related to ablation success rates (p = 0.34), recurrence-free survival (p = 0.29) or DTC -elated mortality (p = 0.82), but established risk factors such as T-stage, lymph node metastases and age were. Ablation was successful in 230 of 275 patients (83.6 %) with TSH <30 mU/l and in 1,359 of 1,598 patients (85.0 %) with TSH ≥30 mU/l. The difference was not significant (p = 0.55). Of the whole group of 1,873 patients, 21 had recurrent disease. There were no significant differences in recurrence rates between patients with TSH <30 mU/l and TSH ≥30 mU/l (p = 0.16). Ten of the 1,873 patients died of DTC. There were no significant differences in DTC-specific survival between patients with TSH <30 mU/l and TSH ≥30 mU/l (p = 0.53).

conclusionThe precise endogenous TSH levels at the time of

Indexed as

131I AblationDifferentiated thyroid cancerPrognosisTSH levels

Identifiers

What OpenQuestion holds

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Read underepoch 390

Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.