Evidence map›Paper›PMID 26492880›Full record

ArticleDysphagia2015

Videofluoroscopic Predictors of Penetration-Aspiration in Parkinson's Disease Patients.

Natalie Argolo, Marília Sampaio, Patrícia Pinho, Ailton Melo, Ana Caline Nóbrega

Registry-linked trialAbstract read
PubMed Publisher
In one paragraph

Article in Dysphagia, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT04928079 (6-year Follow-up of Dysphagia in Patients With Parkinson's Disease), which is not on this map. Cited by 26 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
26citing papers in PubMed, 1 pooled it
7.1field-weighted citation impact, top 4% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT04928079 unknown statusnot on this map

6-year Follow-up of Dysphagia in Patients With Parkinson's Disease

TypeobservationalSponsorSecond Affiliated Hospital, Zhejiang University, School of MedicineRan2014 to 2021Enrolled116ConditionsParkinson Disease, DysphagiaArmsdeep brain stimulation, Anti-Parkinsonian Drugs
3 · Its place in the literature

Who cites it

26 citing papers in PubMed, 1 synthesis or guideline pooled it, 55 citations in OpenAlex.

  1. Pooled it
  2. Breath-Holding Maneuvers and Airway Closure in Healthy Adults and Parkinson's Disease: Effects of Maneuver Type, Health Status, and Vocal Fold Bowing.Folia phoniatrica et logopaedica : official organ of the International Association of Logopedics and Phoniatrics (IALP) · 2025
    Article
  3. Swallow sound acoustics: a cost-effective objective tool for swallowing assessment in individuals with neurogenic dysphagia.Neurological sciences : official journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology · 2025
    Article
  4. Correlation between voice intensity and swallowing function in subjects with Parkinson's disease.Neurological sciences : official journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology · 2025
    Article
  5. Review
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  11. Review
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  14. Review
  15. THE DYSPHAGIA INVESTIGATION: IS THERE STILL SPACE FOR THE VIDEOFLUOROSCOPIC METHOD?Arquivos brasileiros de cirurgia digestiva : ABCD = Brazilian archives of digestive surgery · 2022
    Article
  16. Gray and White Matter Correlates of Dysphagia in Progressive Supranuclear Palsy.Movement disorders : official journal of the Movement Disorder Society · 2021
    Article
  17. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 1 institution in 1 country.

Natalie ArgoloDivision of Neurology and Epidemiology, Federal University of Bahia, Rua Padre Feijó, 29 (4° floor) - Canela, Salvador, Bahia, 40.110-170, Brazil. nataliefono@gmail.com.
Marília SampaioDivision of Neurology and Epidemiology, Federal University of Bahia, Rua Padre Feijó, 29 (4° floor) - Canela, Salvador, Bahia, 40.110-170, Brazil.
Patrícia PinhoDivision of Neurology and Epidemiology, Federal University of Bahia, Rua Padre Feijó, 29 (4° floor) - Canela, Salvador, Bahia, 40.110-170, Brazil.
Ailton MeloDivision of Neurology and Epidemiology, Federal University of Bahia, Rua Padre Feijó, 29 (4° floor) - Canela, Salvador, Bahia, 40.110-170, Brazil.
Ana Caline NóbregaDivision of Neurology and Epidemiology, Federal University of Bahia, Rua Padre Feijó, 29 (4° floor) - Canela, Salvador, Bahia, 40.110-170, Brazil.
Universidade Federal da Bahia · BR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Parkinson's disease (PD) patients show a high prevalence of swallowing disorders and tracheal aspiration of food. The videofluoroscopic study of swallowing (VFSS) allows clinicians to visualize the visuoperceptual and temporal parameters associated with swallowing disorders in an attempt to predict aspiration risk. However, this subject remains understudied in PD populations. Our aim was to identify the predictors of penetration-aspiration in PD patients using the VFSS. Consecutive patients were evaluated using VFSS with different consistencies and volumes of food. A speech-language pathologist measured the type of intra-oral bolus organization, loss of bolus control, bolus location at the initiation of the pharyngeal swallow, the presence of multiple swallows, piecemeal deglutition, bolus residue in the pharyngeal recesses and temporal measures. Scores ≥3 on the penetration-aspiration scale (PAS) indicated the occurrence of penetration-aspiration. Using logistic marginal regression, we found that residue in the vallecula, residue in the upper esophageal sphincter and piecemeal deglutition were associated with penetration-aspiration (odds ratio (OR) = 4.09, 2.87 and 3.83; P = 0.0040, 0.0071 and 0.0009, respectively). Penetration/aspiration occurred only with fluids (both of thin and thick consistency), and no significant differences were observed between fluid types or food volumes. The mechanisms underlying dysphagia and penetration/aspiration in PD patients and indications for further studies are discussed.

Indexed as

Video RecordingBrazilDeglutition DisordersFemaleFluoroscopyHumansIncidenceMaleMiddle AgedNasopharynxParkinson DiseaseRespiratory AspirationDeglutition disordersParkinson’s diseasePenetration/aspiration

Identifiers

PMID26492880
OpenAlexW1880501929

What OpenQuestion holds

Textmetadata
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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.