ArticleScientific reports2015
One-step large-scale deposition of salt-free DNA origami nanostructures.
Article in Scientific reports, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 24 papers.
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Who cites it
24 citing papers in PubMed.
- Tunable fluorogenic DNA probes drive fast and high-resolution single-molecule fluorescence imaging.Nucleic acids research · 2025Article
- Fluorescence Anisotropy for Detailed Analysis of Doxorubicin Loading into DNA Origami Nanocarriers for Drug Delivery.ACS applied nano materials · 2025Article
- Doxorubicin-loaded DNA origami nanostructures: stability in vitreous and their uptake and toxicity in ocular cells.Nanoscale · 2024Article
- Improving DNA nanostructure stability: A review of the biomedical applications and approaches.International journal of biological macromolecules · 2024Review
- Self-Assembly of DNA Nanostructures in Different Cations.Small (Weinheim an der Bergstrasse, Germany) · 2023Article
- Self-assembly of DNA nanostructures in different cations.bioRxiv : the preprint server for biology · 2023Article
- Protein Coating of DNA Origami.Methods in molecular biology (Clifton, N.J.) · 2023Article
- Peptide-DNA origami as a cryoprotectant for cell preservation.Science advances · 2022Article
- Time-Dependent DNA Origami Denaturation by Guanidinium Chloride, Guanidinium Sulfate, and Guanidinium Thiocyanate.International journal of molecular sciences · 2022Article
- Bottom-Up Fabrication of DNA-Templated Electronic Nanomaterials and Their Characterization.Nanomaterials (Basel, Switzerland) · 2021Review
- A Janus-Type Phthalocyanine for the Assembly of Photoactive DNA Origami Coatings.Bioconjugate chemistry · 2021Article
- Hybrid Nanoassemblies from Viruses and DNA Nanostructures.Nanomaterials (Basel, Switzerland) · 2021Review
- Challenges and Perspectives of DNA Nanostructures in Biomedicine.Angewandte Chemie (International ed. in English) · 2020Review
- Increasing Complexity in Wireframe DNA Nanostructures.Molecules (Basel, Switzerland) · 2020Review
- Photocontrolled Dopamine Polymerization on DNA Origami with Nanometer Resolution.Angewandte Chemie (International ed. in English) · 2020Article
- Electrostatically PEGylated DNA enables salt-free hybridization in water.Chemical science · 2019Article
- Effect of Staple Age on DNA Origami Nanostructure Assembly and Stability.Molecules (Basel, Switzerland) · 2019Article
- Cationic Albumin Encapsulated DNA Origami for Enhanced Cellular Transfection and Stability.Materials (Basel, Switzerland) · 2019Article
- DNA Origami Nanophotonics and Plasmonics at Interfaces.Langmuir : the ACS journal of surfaces and colloids · 2018Article
- Superstructure-Dependent Loading of DNA Origami Nanostructures with a Groove-Binding Drug.ACS omega · 2018Article
Corrections and comments
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Authors and funding
6 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
DNA origami nanostructures have tremendous potential to serve as versatile platforms in self-assembly -based nanofabrication and in highly parallel nanoscale patterning. However, uniform deposition and reliable anchoring of DNA nanostructures often requires specific conditions, such as pre-treatment of the chosen substrate or a fine-tuned salt concentration for the deposition buffer. In addition, currently available deposition techniques are suitable merely for small scales. In this article, we exploit a spray-coating technique in order to resolve the aforementioned issues in the deposition of different 2D and 3D DNA origami nanostructures. We show that purified DNA origamis can be controllably deposited on silicon and glass substrates by the proposed method. The results are verified using either atomic force microscopy or fluorescence microscopy depending on the shape of the DNA origami. DNA origamis are successfully deposited onto untreated substrates with surface coverage of about 4 objects/mm(2). Further, the DNA nanostructures maintain their shape even if the salt residues are removed from the DNA origami fabrication buffer after the folding procedure. We believe that the presented one-step spray-coating method will find use in various fields of material sciences, especially in the development of DNA biochips and in the fabrication of metamaterials and plasmonic devices through DNA metallisation.
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