ArticlePloS one2015
Frequency of and Risk Factors for Depression among Participants in the Swiss HIV Cohort Study (SHCS).
Article in PloS one, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers, 1 of them a synthesis that pooled it.
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Who cites it
19 citing papers in PubMed, 1 synthesis or guideline pooled it, 48 citations in OpenAlex.
- Psychosocial group interventions to improve psychological well-being in adults living with HIV.The Cochrane database of systematic reviews · 2017Pooled it
- Assessing incident depression among older people with and without HIV in U.S.Social psychiatry and psychiatric epidemiology · 2023Article
- Article
- Predicting the presence of depressive symptoms in the HIV-HCV co-infected population in Canada using supervised machine learning.BMC medical research methodology · 2022Article
- Glutamine antagonist JHU083 improves psychosocial behavior and sleep deficits in EcoHIV-infected mice.Brain, behavior, & immunity - health · 2022Article
- The Role of Online Support Groups in Helping Individuals Affected by HIV and AIDS: Scoping Review of the Literature.Journal of medical Internet research · 2022Article
- Neutral sphingomyelinase 2 inhibition attenuates extracellular vesicle release and improves neurobehavioral deficits in murine HIV.Neurobiology of disease · 2022Article
- The role of depression in secondary HIV transmission among people who inject drugs in Vietnam: A mathematical modeling analysis.PloS one · 2022Article
- Race-Dependent Association of Single-Nucleotide Polymorphisms in TrkB Receptor in People Living with HIV and Depression.Neurotoxicity research · 2021Article
- Article
- Low Neuroactive Steroids Identifies a Biological Subtype of Depression in Adults with Human Immunodeficiency Virus on Suppressive Antiretroviral Therapy.The Journal of infectious diseases · 2021Article
- Depression, antiretroviral therapy initiation, and HIV viral suppression among people who inject drugs in Vietnam.Journal of affective disorders · 2021Article
- Estimating the Effect of Depression on HIV Transmission Risk Behaviors Among People Who Inject Drugs in Vietnam: A Causal Approach.AIDS and behavior · 2021Article
- Mortality from suicide among people living with HIV and the general Swiss population: 1988-2017.Journal of the International AIDS Society · 2019Article
- A Cross Sectional Examination of the Relation Between Depression and Frequency of Leisure Time Physical Exercise among the Elderly in Jinan, China.International journal of environmental research and public health · 2018Article
- Emotional Availability, Neuropsychological Functioning, and Psychopathology: The Context of Parental Substance Use Disorder.BioMed research international · 2018Article
- Prevalence and predictors of depressive symptoms among HIV-positive men who inject drugs in Vietnam.PloS one · 2018Article
- Longitudinal Modeling of Depressive Trajectories Among HIV-Infected Men Using Cocaine.AIDS and behavior · 2017Article
- Article
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Authors and funding
12 authors at 9 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
objectivesWe studied the incidence and prevalence of, and co-factors for depression in the Swiss HIV Cohort Study.
methodsDepression-specific items were introduced in 2010 and prospectively collected at semiannual cohort visits. Clinical, laboratory and behavioral co-factors of incident depression among participants free of depression at the first two visits in 2010 or thereafter were analyzed with Poisson regression. Cumulative prevalence of depression at the last visit was analyzed with logistic regression.
resultsAmong 4,422 participants without a history of psychiatric disorders or depression at baseline, 360 developed depression during 9,348 person-years (PY) of follow-up, resulting in an incidence rate of 3.9 per 100 PY (95% confidence interval (CI) 3.5-4.3). Cumulative prevalence of depression during follow-up was recorded for 1,937/6,756 (28.7%) participants. Incidence and cumulative prevalence were higher in injection drug users (IDU) and women. Older age, preserved work ability and higher physical activity were associated with less depression episodes. Mortality (0.96 per 100 PY, 95% CI 0.83-1.11) based upon 193 deaths over 20,102 PY was higher among male IDU (2.34, 1.78-3.09), female IDU (2.33, 1.59-3.39) and white heterosexual men (1.32, 0.94-1.84) compared to white heterosexual women and homosexual men (0.53, 0.29-0.95; and 0.71, 0.55-0.92). Compared to participants free of depression, mortality was slightly elevated among participants with a history of depression (1.17, 0.94-1.45 vs. 0.86, 0.71-1.03, P = 0.033). Suicides (n = 18) did not differ between HIV transmission groups (P = 0.50), but were more frequent among participants with a prior diagnosis of depression (0.18 per 100 PY, 95%CI 0.10-0.31; vs. 0.04, 0.02-0.10; P = 0.003).
conclusionsDepression is a frequent co-morbidity among HIV-infected persons, and thus an important focus of care.
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