Evidence map›Paper›PMID 26492369›Full record

ArticleCell death & disease2015

Reactivation of p53 via MDM2 inhibition.

E S Kim, J M Shohet

Abstract read
In one paragraph

Article in Cell death & disease, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed.

  1. SNPs Give LACTB Oncogene-Like Functions and Prompt Tumor Progression via Dual-Regulating p53.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2024
    Article
  2. MDM2 amplification is rare in gastric cancer.Virchows Archiv : an international journal of pathology · 2023
    Article
  3. Review
  4. Emerging roles of Myc in stem cell biology and novel tumor therapies.Journal of experimental & clinical cancer research : CR · 2018
    Review
  5. Article
  6. Analysis ofJCO precision oncology · 2018
    Article
  7. Review
  8. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

E S KimDivision of Pediatric Surgery, Department of Surgery, Keck School of Medicine, University of Southern California, Los Angeles, CA 90027, USA.
J M ShohetDepartment of Pediatrics, Section of Hematology-Oncology, Texas Children's Cancer Center, and Center for Cell and Gene Therapy, Baylor College of Medicine, Houston, TX 77030, USA.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

AnimalsApoptosisCell Line, TumorHypoxia-Inducible Factor 1, alpha SubunitMiceNeovascularization, PathologicNeuroblastomapara-AminobenzoatesProto-Oncogene Proteins c-mdm2PyrrolidinesTumor Suppressor Protein p53Vascular Endothelial Growth Factor AHypoxia-Inducible Factor 1, alpha Subunitpara-AminobenzoatesProto-Oncogene Proteins c-mdm2PyrrolidinesRG7388Tumor Suppressor Protein p53Vascular Endothelial Growth Factor A

Identifiers

PMID26492369
PMCPMC4632320

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.