Evidence map›Paper›PMID 26492328›Full record

ArticleAlzheimer disease and associated disorders

Same Ages, Same Genes: Same Brains, Same Pathologies?: Dementia Timings, Co-Occurring Brain Pathologies, ApoE Genotypes in Identical and Fraternal Age-matched Twins at Autopsy.

Diego Iacono, Inga Volkmann, Inger Nennesmo, Nancy L Pedersen, Laura Fratiglioni, Boo Johansson, David Karlsson, Bengt Winblad, Margaret Gatz

Abstract readTwin Study
PubMed Full text at PMC Publisher
In one paragraph

Article in Alzheimer disease and associated disorders. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Diego Iacono*Department NVS, Center for Alzheimer Research, Division of Neurogeriatrics, Karolinska Institutet, Huddinge∥Department of Pathology, Karolinska University Hospital¶Department of Medical Epidemiology and Biostatistics, Karolinska Institutet#Aging Research Center (ARC), Karolinska Institutet/Stockholm University, Stockholm**Department of Psychology, University of Göthenburg, Göthenburg††Department of Geriatric Rehabilitation, Värnamo Hospital, Värnamo, Sweden†Neuropathology Research, Biomedical Research Institute of New Jersey, BRInj, Cedar Knolls‡Atlantic Neuroscience Institute, Atlantic Health System, Overlook and Morristown Medical Center, Morristown, NJ§Department of Neurology, Icahn School of Medicine at Mount Sinai, New York, NY‡‡Department of Psychology, University of Southern California, Los Angeles, CA.
Inga Volkmann
Inger Nennesmo
Nancy L Pedersen
Laura Fratiglioni
Boo Johansson
David Karlsson
Bengt Winblad
Margaret Gatz

Funding

GENETIC &ENVIRONMENTAL INFLUENCES--BIOBEHAVIORAL AGINGR01AG010175 · NIA · UNIVERSITY OF SOUTHERN CALIFORNIA · PI PEDERSEN, NANCY L · 1992 to 2006
$2.8M
DEMENTIA IN TWINSR01AG008724 · NIA · UNIVERSITY OF SOUTHERN CALIFORNIA · PI GATZ, MARGARET · 1990 to 2002
$1.4M
Dementia in Swedish Twins Data ArchivingR03AG031262 · NIA · UNIVERSITY OF SOUTHERN CALIFORNIA · PI GATZ, MARGARET · 2008 to 2008
$72k
NIA NIH HHS R01 AG008724NIA NIH HHS R01 AG010175NIA NIH HHS R03 AG031262
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

AgedAged, 80 and overAgingApolipoproteins EAutopsyBrainDementiaFemaleHumansMaleTwins, DizygoticTwins, MonozygoticApolipoproteins E

Identifiers

PMID26492328
PMCPMC4840096

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.