ReviewBiomolecules2015
Chronic Ethanol Exposure: Pathogenesis of Pulmonary Disease and Dysfunction.
Review in Biomolecules, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers, 2 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
16 citing papers in PubMed, 2 syntheses or guidelines pooled it, 28 citations in OpenAlex.
- A review of the relationship between dimensions of alcohol consumption and the burden of disease: 2026 update including Mendelian randomisation studies.Addiction (Abingdon, England) · 2026Pooled it
- The relationship between different dimensions of alcohol use and the burden of disease-an update.Addiction (Abingdon, England) · 2017Pooled it
- Trial
- NMR Profiling of Exhaled Breath Condensate Defines Different Metabolic Phenotypes of Non-Cystic Fibrosis Bronchiectasis.International journal of molecular sciences · 2020Trial
- Purinergic and extracellular vesicle signaling in alcohol-induced blood-brain barrier breakdown and neuroimmune activation.Brain, behavior, and immunity · 2025Review
- Nationwide Trends and Outcomes of Alcohol Use Disorders in COPD Hospitalizations in Spain, 2016-2023.Journal of clinical medicine · 2025Article
- Histological and Immunohistochemical Evidence in Hypothermia-Related Death: An Experimental Study.International journal of molecular sciences · 2025Article
- Pulmonary Complications of Substance Abuse: Pathophysiology, Diagnosis, and Management Strategies.Addiction & health · 2025Review
- Alcohol Vapor Sensor Based on Quasi-2D NbSensors (Basel, Switzerland) · 2023Article
- Ketamine plus Alcohol: What We Know and What We Can Expect about This.International journal of molecular sciences · 2022Review
- Zinc Prevents Ethanol-Induced Oxidative Damage in Lingual Tissues of Rats.Biological trace element research · 2022Article
- Influence of Cigarettes and Alcohol on the Severity and Death of COVID-19: A Multicenter Retrospective Study in Wuhan, China.Frontiers in physiology · 2020Article
- Persistence of Burkholderia thailandensis E264 in lung tissue after a single binge alcohol episode.PloS one · 2019Article
- Article
- Platelet Endothelial Cell Adhesion Molecule-1 and Oligodendrogenesis: Significance in Alcohol Use Disorders.Brain sciences · 2017Review
- Multi-Organ Alcohol-Related Damage: Mechanisms and Treatment.Biomolecules · 2016Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
3 authors at 1 institution in 1 country.
Funding
Abstract
Ethanol (EtOH) is the world's most commonly used drug, and has been widely recognized as a risk factor for developing lung disorders. Chronic EtOH exposure affects all of the organ systems in the body and increases the risk of developing pulmonary diseases such as acute lung injury and pneumonia, while exacerbating the symptoms and resulting in increased mortality in many other lung disorders. EtOH and its metabolites inhibit the immune response of alveolar macrophages (AMs), increase airway leakage, produce damaging reactive oxygen species (ROS), and disrupt the balance of antioxidants/oxidants within the lungs. In this article, we review the role of EtOH exposure in the pathogenesis and progression of pulmonary disease.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.