ArticleMarine drugs2015
Assessment of the Antimicrobial Activity of Algae Extracts on Bacteria Responsible of External Otitis.
Article in Marine drugs, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers.
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Who cites it
17 citing papers in PubMed.
- Microalgae-Based Disinfectant Formulation for Aseptic Processing of Ethiopian Ingredient-Sourced Functional Bread and Its Molecular Docking Analysis to Reduce Hypernatremia.Molecular biotechnology · 2026Article
- Aetiologies of Ear Infections Among Patients Who Visited King Fahad Hospital in Al-Baha, Saudi Arabia.Cureus · 2024Article
- Antimicrobial Activity ofInternational journal of molecular sciences · 2024Review
- Microalgal bioactive metabolites as promising implements in nutraceuticals and pharmaceuticals: inspiring therapy for health benefits.Phytochemistry reviews : proceedings of the Phytochemical Society of Europe · 2023Review
- Isolation ofBiotechnology reports (Amsterdam, Netherlands) · 2022Article
- Role of microalgal metabolites in controlling quorum-sensing-regulated biofilm.Archives of microbiology · 2022Review
- Algal polysaccharide's potential to combat respiratory infections caused by Klebsiella pneumoniae and Serratia marcescens biofilms.Applied biochemistry and biotechnology · 2022Article
- Slime molds as a valuable source of antimicrobial agents.AMB Express · 2021Review
- Microalgal Cell Biofactory-Therapeutic, Nutraceutical and Functional Food Applications.Plants (Basel, Switzerland) · 2021Review
- Effectiveness ofPathogens (Basel, Switzerland) · 2020Article
- Deciphering the Biological Activities ofInternational journal of molecular sciences · 2020Article
- Review on Natural Preservatives for Extending Fish Shelf Life.Foods (Basel, Switzerland) · 2019Review
- Identification of Antimicrobial Peptides from the MicroalgaeMarine drugs · 2019Article
- The promising future of microalgae: current status, challenges, and optimization of a sustainable and renewable industry for biofuels, feed, and other products.Microbial cell factories · 2018Review
- First identification of marine diatoms with anti-tuberculosis activity.Scientific reports · 2018Article
- Antimicrobial Compounds from Eukaryotic Microalgae against Human Pathogens and Diseases in Aquaculture.Marine drugs · 2016Review
- Review
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Authors and funding
5 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
External otitis is a diffuse inflammation around the external auditory canal and auricle, which is often occurred by microbial infection. This disease is generally treated using antibiotics, but the frequent occurrence of antibiotic resistance requires the development of new antibiotic agents. In this context, unexplored bioactive natural candidates could be a chance for the production of targeted drugs provided with antimicrobial activity. In this paper, microbial pathogens were isolated from patients with external otitis using ear swabs for over one year, and the antimicrobial activity of the two methanol extracts from selected marine (Dunaliella salina) and freshwater (Pseudokirchneriella subcapitata) microalgae was tested on the isolated pathogens. Totally, 114 bacterial and 11 fungal strains were isolated, of which Staphylococcus spp. (28.8%) and Pseudomonas aeruginosa (P. aeruginosa) (24.8%) were the major pathogens. Only three Staphylococcus aureus (S. aureus) strains and 11 coagulase-negative Staphylococci showed resistance to methicillin. The two algal extracts showed interesting antimicrobial properties, which mostly inhibited the growth of isolated S. aureus, P. aeruginosa, Escherichia coli, and Klebsiella spp. with MICs range of 1.4 × 10⁸ to 2.2 × 10(10) cells/mL. These results suggest that the two algae have potential as resources for the development of antimicrobial agents.
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