SynthesisBioMed research international2015
Comparison of Fine Needle Aspiration and Fine Needle Nonaspiration Cytology of Thyroid Nodules: A Meta-Analysis.
Synthesis in BioMed research international, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.
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Who cites it
10 citing papers in PubMed.
- Comparison of two puncture techniques for fine-needle capillary biopsy in thyroid nodules: a randomized controlled trial.Endocrine journal · 2026Trial
- Article
- Assessment of an innovative synthetic matrix for enhanced cell preservation: evaluating its clinical utility and impact on diagnostic precision in thyroid fine-needle aspiration cytology.BMC endocrine disorders · 2026Article
- Current role of interventional radiology in thyroid nodules.Frontiers in endocrinology · 2024Review
- Comparison of fine-needle aspiration with fine-needle capillary cytology in thyroid nodules.Annals of the Royal College of Surgeons of England · 2023Article
- Analysis of the influencing factors on fine-needle aspiration biopsy results of the thyroid.Frontiers in surgery · 2022Article
- Comparison of Ultrasound-Guided Fine-Needle Cytology Quality in Thyroid Nodules with 22-, 23-, and 25-Gauge Needles.Analytical cellular pathology (Amsterdam) · 2021Article
- Comprehensive evaluation of medullary thyroid carcinoma before surgery.Chinese medical journal · 2019Article
- Diagnostic validity of fine-needle capillary cytology in palpable tumours at the Oncology Institute of Peru.Ecancermedicalscience · 2018Article
- Examination of Selective Low-pressure Fine Needle Aspiration Cytology Under Ultrasound Guidance.Yonago acta medica · 2017Article
Corrections and comments
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Authors and funding
7 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundFine needle aspiration cytology (FNAC) and fine needle nonaspiration cytology (FNNAC) are useful cost-effective techniques for preoperatively assessing thyroid lesions. Both techniques have advantages and disadvantages, and there is controversy over which method is superior. This meta-analysis was performed to evaluate the differences between FNAC and FNNAC for diagnosis of thyroid nodules.
methodsPrimary publications were independently collected by two reviewers from PubMed, Web of Science, Google Scholar, EBSCO, OALib, and the Cochrane Library databases. The following search terms were used: fine needle, aspiration, capillary, nonaspiration, sampling without aspiration, thyroid, and cytology. The last search was performed on February 1, 2015.
resultsSixteen studies comprising 1,842 patients and 2,221 samples were included in this study. No statistically significant difference was observed between FNAC and FNNAC groups with respect to diagnostically inadequate smears, diagnostically superior smears, diagnostic performance (accuracy, sensitivity, specificity, negative predictive value, and positive predictive value), area under the summary receiver operating characteristic curve, average score of each parameter (background blood or clot, amount of cellular material, degree of cellular degeneration, degree of cellular trauma, and retention of appropriate architecture), and total score of five parameters.
conclusionFNAC and FNNAC are equally useful in assessing thyroid nodules.
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