ReviewBioMed research international2015
Past, Present, and Future of Nerve Conduits in the Treatment of Peripheral Nerve Injury.
Review in BioMed research international, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 79 papers, 2 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
79 citing papers in PubMed, 2 syntheses or guidelines pooled it, 191 citations in OpenAlex.
- Systematic review of the therapeutic use of Schwann cells in the repair of peripheral nerve injuries: Advancements from animal studies to clinical trials.Frontiers in cellular neuroscience · 2022Pooled it
- Identification of potential microRNAs and KEGG pathways in denervation muscle atrophy based on meta-analysis.Scientific reports · 2021Pooled it
- Smart-responsive electrospun scaffolds (SRES) for neural repair: Recent advances and future prospects.Bioactive materials · 2026Review
- Nerve Cell Responses to Biocompatible RGO-Chitosan-CMC Nanofiber Composite Membranes.International journal of molecular sciences · 2026Article
- Aging-Related Changes in the Injury Response of the Peripheral Nervous System.Neuroscience bulletin · 2026Review
- Delayed repair of singly transected and segmental-loss peripheral nerve injuries in rat sciatic nerves using optimized PEG-fusion protocols and stored viable peripheral nerve allografts.Journal of translational medicine · 2026Article
- Successful polyethylene glycol fusion repair using stored viable peripheral nerve allografts in Sprague-Dawley and Lewis rats.Neural regeneration research · 2026Article
- In Vivo Evaluation of Conductive Biopolymer-Based 3D Bioprinted Nerve Conduit in Sciatic Nerve Injury Repair.Macromolecular bioscience · 2026Article
- A Sutureless Approach to Nerve Repair: Results From a Clinical Study in Digital Nerves.Journal of hand surgery global online · 2026Article
- PEG-Fusion Repair After Peripheral Nerve Injuries Enhances Behavioral Recovery and Reduces Self-Mutilation in Rat Models.Neurology international · 2026Article
- Reconstructive Techniques and Outcomes for Large (≥4 cm) Peripheral Nerve Defects: A Meta-analysis.Plastic and reconstructive surgery. Global open · 2026Article
- Structural Features of Nerve Guidance Conduits and Scaffolds in Preventing Axonal Misdirection: A Systematic Review of Retrograde Tracing Studies.Bioengineering (Basel, Switzerland) · 2026Review
- Mesenchymal stem cell-laden double-network hydrogel nerve guidance conduits for peripheral nerve injury repair.Bioactive materials · 2025Article
- Revolutionizing nerve regeneration: A novel approach using polylactic acid/chitosan conduit with nerve-like cells andRegenerative therapy · 2025Article
- Peripheral Nerve Regeneration Reimagined: Cutting-Edge Biomaterials and Biotechnological Innovations.Bioengineering (Basel, Switzerland) · 2025Review
- Review
- Managing surface energy dynamics for enhanced axonal growth: An overview of present and future challenges.Biophysics reviews · 2025Review
- Article
- Optimizing Peripheral Nerve Regeneration: Surgical Techniques, Biomolecular and Regenerative Strategies-A Narrative Review.International journal of molecular sciences · 2025Review
- 3D printed biodegradable hydrogel-based multichannel nerve conduits mimicking peripheral nerve fascicules.Materials today. Bio · 2025Article
19 more citing papers are in PubMed but not listed here.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
2 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
With significant advances in the research and application of nerve conduits, they have been used to repair peripheral nerve injury for several decades. Nerve conduits range from biological tubes to synthetic tubes, and from nondegradable tubes to biodegradable tubes. Researchers have explored hollow tubes, tubes filled with scaffolds containing neurotrophic factors, and those seeded with Schwann cells or stem cells. The therapeutic effect of nerve conduits is improving with increasing choice of conduit material, new construction of conduits, and the inclusion of neurotrophic factors and support cells in the conduits. Improvements in functional outcomes are expected when these are optimized for use in clinical practice.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.