ReviewMedical devices (Auckland, N.Z.)2015
Critical review of the responsive neurostimulator system for epilepsy.
Review in Medical devices (Auckland, N.Z.), 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 48 papers, 1 of them a synthesis that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
48 citing papers in PubMed, 1 synthesis or guideline pooled it, 131 citations in OpenAlex.
- Evidence-Based Guidelines and Secondary Meta-Analysis for the Use of Transcranial Direct Current Stimulation in Neurological and Psychiatric Disorders.The international journal of neuropsychopharmacology · 2021Pooled it
- Gamma suppression correlates with thalamic stimulation therapeutic response in intractable epilepsy.Epilepsia · 2026Article
- Stabilizing fractional dynamical networks suppresses epileptic seizures.Scientific reports · 2026Article
- Stable, chronic in-vivo recordings from a fully wireless subdural-contained 65,536-electrode brain-computer interface device.bioRxiv : the preprint server for biology · 2025Article
- Article
- Network excitability of stimulation-induced spectral responses helps localize the seizure onset zone.Clinical neurophysiology : official journal of the International Federation of Clinical Neurophysiology · 2024Article
- Role of Responsive Neurostimulation in Managing Drug-Resistant Epilepsy: A Systematic Review of Clinical Outcomes.Cureus · 2024Review
- Miniature battery-free epidural cortical stimulators.Science advances · 2024Article
- Fabrication and Validation of Sub-Cellular Carbon Fiber Electrodes.IEEE transactions on neural systems and rehabilitation engineering : a publication of the IEEE Engineering in Medicine and Biology Society · 2024Article
- Novel Surgical Approaches in Childhood Epilepsy: Laser, Brain Stimulation, and Focused Ultrasound.Advances and technical standards in neurosurgery · 2024Article
- Effective connectivity relates seizure outcome to electrode placement in responsive neurostimulation.Brain communications · 2024Article
- Quantitative approaches to guide epilepsy surgery from intracranial EEG.Brain : a journal of neurology · 2023Article
- Vasospasm secondary to responsive neurostimulator placement: a previously unreported complication. Illustrative case.Journal of neurosurgery. Case lessons · 2023Article
- Quantifying trial-by-trial variability during cortico-cortical evoked potential mapping of epileptogenic tissue.Epilepsia · 2023Article
- Targeted neuroplasticity in spatiotemporally patterned invasive neuromodulation therapies for improving clinical outcomes.Frontiers in neuroinformatics · 2023Article
- Ultrasonic therapies for seizures and drug-resistant epilepsy.Frontiers in neurology · 2023Review
- Resection of an occipital lobe epileptogenic network resulting in improvement of a visual field deficit: illustrative case.Journal of neurosurgery. Case lessons · 2022Article
- Implementation of a Morphological Filter for Removing Spikes from the Epileptic Brain Signals to Improve Identification Ripples.Sensors (Basel, Switzerland) · 2022Article
- Brain-machine-brain interfaces as the foundation for the next generation of neuroprostheses.National science review · 2022Article
- Future opportunities for research in rescue treatments.Epilepsia · 2022Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
2 authors at 2 institutions in 1 country.
Funding
Abstract
Patients with medically refractory epilepsy have historically had few effective treatment options. Electrical brain stimulation for seizures has been studied for decades and ongoing technological refinements have made possible the development of an implantable electrical brain stimulator. The NeuroPace responsive neurostimulator was recently approved by the FDA for clinical use and the initial reports are encouraging. This device continually monitors brain activity and delivers an electric stimulus when abnormal activity is detected. Early reports of efficacy suggest that the device is well tolerated and offers a reduction in seizure frequency by approximately half at 2 years.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.