ArticleTherapeutics and clinical risk management2015
Acute gastrointestinal injury in the intensive care unit: a retrospective study.
Article in Therapeutics and clinical risk management, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers, 1 of them a synthesis that pooled it.
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Who cites it
16 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Prevalence and outcome of acute gastrointestinal injury in critically ill patients: A systematic review and meta-analysis.Medicine · 2018Pooled it
- Article
- Inulin promotes appetite in mice by regulating the gut microbiota under conditions of rapid entry to the plateau.PloS one · 2025Article
- Prognostic risk factors in upper gastrointestinal perforation: the role of body composition parameters.Frontiers in nutrition · 2025Article
- Prognostic impact of postoperative management by an intensive care unit intensivist after colonic perforation.Langenbeck's archives of surgery · 2024Article
- Ventilatory pressure parameters impact the association between acute gastrointestinal injury and all-cause mortality in mechanically ventilated patients.Scientific reports · 2024Observational
- Synergizing Survival: Uniting Acute Gastrointestinal Injury Grade and Disease Severity Scores in Critical Care Prognostication.Indian journal of critical care medicine : peer-reviewed, official publication of Indian Society of Critical Care Medicine · 2024Article
- Prognostic Value of Acute Gastrointestinal Injury Combined with Disease Severity Scores in Critically Ill Patients.Indian journal of critical care medicine : peer-reviewed, official publication of Indian Society of Critical Care Medicine · 2024Article
- Article
- Polysaccharide-Based Multifunctional Hydrogel Bio-Adhesives for Wound Healing: A Review.Gels (Basel, Switzerland) · 2023Review
- Risk Factors of Gastrointestinal Perforation with a Poor Prognosis.International journal of general medicine · 2023Article
- Role of heparinase in the gastrointestinal dysfunction of sepsis (Review).Experimental and therapeutic medicine · 2022Review
- Omega-3 fatty acids impair miR-1-3p-dependent Notch3 down-regulation and alleviate sepsis-induced intestinal injury.Molecular medicine (Cambridge, Mass.) · 2022Article
- Construction and efficacy evaluation of an early warning scoring system for septic shock in patients with digestive tract perforation: A retrospective cohort study.Frontiers in medicine · 2022Article
- Risk factors for postoperative sepsis in patients with gastrointestinal perforation.World journal of clinical cases · 2020Article
- Guiding Management in Severe Trauma: Reviewing Factors Predicting Outcome in Vastly Injured Patients.Journal of emergencies, trauma, and shockReview
Corrections and comments
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5 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundAcute gastrointestinal injury (AGI) is a common problem in the intensive care unit (ICU). This study is a review of the gastrointestinal function of patients in critical care, with the aim to assess the feasibility and effectiveness of grading criteria developed by the European Society of Intensive Care Medicine (ESICM) Working Group on Abdominal Problems (WGAP).
methodsData of patients who were admitted to the ICU of Shenzhen People's Hospital, Shenzhen, People's Republic of China, from January 2010 to December 2011 were reviewed. A total of 874 patients were included into the current study. Their sex, age, ICU admissive causes, complication of diabetes, AGI grade, primary or secondary AGI, mechanical ventilation (MV), and length of ICU stay (days) were recorded as risk factors of death. These risk factors were studied by unconditioned logistic regression analysis.
resultsAll the risk factors affected mortality rate. Unconditional logistic regression analysis revealed that the mortality rate of secondary AGI was 71 times higher than primary AGI (odds ratio [OR] 4.335, 95% CI [1.652, 11.375]). When the age increased by one year, the mortality probability would increase fourfold. Mortality in patients with MV was 63-fold higher than for patients with non-MV. Mortality rate increased 0.978 times with each additional day of ICU stay.
conclusionSecondary AGI caused by severe systemic conditions can result in worsened clinical outcomes. The 2012 ESICM WGAP AGI recommendations were to some extent feasible and effective in guiding clinical practices, but the grading system lacked the support of objective laboratory outcomes.
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