ArticleJournal of the Royal Society, Interface2015
Peroxidase-catalysed interfacial adhesion of aquatic caddisworm silk.
Article in Journal of the Royal Society, Interface, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
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Who cites it
9 citing papers in PubMed, 25 citations in OpenAlex.
- High Performance Marine and Terrestrial Bioadhesives and the Biomedical Applications They Have Inspired.Molecules (Basel, Switzerland) · 2022Review
- Comprehensive Transcriptome Sequencing of Tanaidacea with Proteomic Evidences for Their Silk.Genome biology and evolution · 2021Article
- Protein Composition and Associated Material Properties of Cobweb Spiders' Gumfoot Glue Droplets.Integrative and comparative biology · 2021Article
- Draft Genome Assemblies and Annotations of Agrypnia vestita Walker, and Hesperophylax magnus Banks Reveal Substantial Repetitive Element Expansion in Tube Case-Making Caddisflies (Insecta: Trichoptera).Genome biology and evolution · 2021Article
- Reversible Oxidative Modifications in Myoglobin and Functional Implications.Antioxidants (Basel, Switzerland) · 2020Article
- The Quantitative Proteome of the Cement and Adhesive Gland of the Pedunculate Barnacle,International journal of molecular sciences · 2020Article
- In Silico Analysis of Pacific Oyster (International journal of molecular sciences · 2019Article
- Sequence basis of Barnacle Cement Nanostructure is Defined by Proteins with Silk Homology.Scientific reports · 2016Article
- Connecting caddisworm silk structure and mechanical properties: combined infrared spectroscopy and mechanical analysis.Open biology · 2016Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
4 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Casemaker caddisfly (Hesperophylax occidentalis) larvae use adhesive silk fibres to construct protective shelters under water. The silk comprises a distinct peripheral coating on a viscoelastic fibre core. Caddisworm silk peroxinectin (csPxt), a haem-peroxidase, was shown to be glycosylated by lectin affinity chromatography and tandem mass spectrometry. Using high-resolution H2O2 and peroxidase-dependent silver ion reduction and nanoparticle deposition, imaged by electron microscopy, csPxt activity was shown to be localized in the peripheral layer of drawn silk fibres. CsPxt catalyses dityrosine cross-linking within the adhesive peripheral layer post-draw, initiated perhaps by H2O2 generated by a silk gland-specific superoxide dismutase 3 (csSOD3) from environmental reactive oxygen species present in natural water. CsSOD3 was also shown to be a glycoprotein and is likely localized in the peripheral layer. Using a synthetic fluorescent phenolic copolymer and confocal microscopy, it was shown that csPxt catalyses oxidative cross-linking to external polyphenolic compounds capable of diffusive interpenetration into the fuzzy peripheral coating, including humic acid, a natural surface-active polyphenol. The results provide evidence of enzyme-mediated covalent cross-linking of a natural bioadhesive to polyphenol conditioned interfaces as a mechanism of permanent adhesion underwater.
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Registered trials
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