ArticleDevelopmental science2017
Splenium development and early spoken language in human infants.
Article in Developmental science, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 39 papers.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
39 citing papers in PubMed, 53 citations in OpenAlex.
- Visual Cortical Response Variability in Infants at High Familial Likelihood for Autism.Developmental science · 2026Article
- Does bilingualism buffer genetic predispositions to reading difficulties through alterations of structural interhemispheric connectivity? An ABCDbioRxiv : the preprint server for biology · 2026Article
- Visual Cortical Response Variability in Infants at High Familial Likelihood for Autism.bioRxiv : the preprint server for biology · 2026Article
- Functional connectivity of the superior temporal sulcus at term-equivalent age: effects of gestational age and sex.Brain structure & function · 2025Article
- Article
- Comparative profiling of white matter development in the human and mouse brain reveals volumetric deficits and delayed myelination in Angelman syndrome.Molecular autism · 2024Article
- Social and Communication Development in Infants with Isolated Agenesis of the Corpus Callosum.Journal of pediatrics. Clinical practice · 2024Article
- Comparative profiling of white matter development in the human and mouse brain reveals volumetric deficits and delayed myelination in Angelman syndrome.Research square · 2024Article
- White matter development and language abilities during infancy in autism spectrum disorder.Molecular psychiatry · 2024Article
- EEG Correlates of Cognitive Functions in a Child with ASD and White Matter Signal Abnormalities: A Case Report with Two-and-a-Half-Year Follow-Up.Diagnostics (Basel, Switzerland) · 2023Article
- Microstructural Alterations in Projection and Association Fibers in Neonatal Hypoxia-Ischemia.Journal of magnetic resonance imaging : JMRI · 2023Article
- Language Experience during Infancy Predicts White Matter Myelination at Age 2 Years.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2023Article
- Article
- Infant Visual Brain Development and Inherited Genetic Liability in Autism.The American journal of psychiatry · 2022Article
- White matter microstructural and morphometric alterations in autism: implications for intellectual capabilities.Molecular autism · 2022Article
- Diffusion Tensor Based White Matter Tract Atlases for Pediatric Populations.Frontiers in neuroscience · 2022Article
- Language input in late infancy scaffolds emergent literacy skills and predicts reading related white matter development.Frontiers in human neuroscience · 2022Article
- Lack of neural evidence for implicit language learning in 9-month-old infants at high risk for autism.Developmental science · 2021Article
- 6q25.1-q25.3 Microdeletion in a Chinese GirlJournal of clinical research in pediatric endocrinology · 2021Article
- Infant and Child MRI: A Review of Scanning Procedures.Frontiers in neuroscience · 2021Review
Corrections and comments
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Authors and funding
15 authors at 6 institutions in 1 country.
Funding
Abstract
The association between developmental trajectories of language-related white matter fiber pathways from 6 to 24 months of age and individual differences in language production at 24 months of age was investigated. The splenium of the corpus callosum, a fiber pathway projecting through the posterior hub of the default mode network to occipital visual areas, was examined as well as pathways implicated in language function in the mature brain, including the arcuate fasciculi, uncinate fasciculi, and inferior longitudinal fasciculi. The hypothesis that the development of neural circuitry supporting domain-general orienting skills would relate to later language performance was tested in a large sample of typically developing infants. The present study included 77 infants with diffusion weighted MRI scans at 6, 12 and 24 months and language assessment at 24 months. The rate of change in splenium development varied significantly as a function of language production, such that children with greater change in fractional anisotropy (FA) from 6 to 24 months produced more words at 24 months. Contrary to findings from older children and adults, significant associations between language production and FA in the arcuate, uncinate, or left inferior longitudinal fasciculi were not observed. The current study highlights the importance of tracing brain development trajectories from infancy to fully elucidate emerging brain-behavior associations while also emphasizing the role of the splenium as a key node in the structural network that supports the acquisition of spoken language.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.