Evidence map›Paper›PMID 26490144›Full record

ArticleJournal of medical systems2015

iMStrong: Deployment of a Biosensor System to Detect Cocaine Use.

Stephanie Carreiro, Hua Fang, Jianying Zhang, Kelley Wittbold, Shicheng Weng, Rachel Mullins, David Smelson, Edward W Boyer

Registry-linked trialAbstract read
In one paragraph

Article in Journal of medical systems, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT07067151 (Use of Noninvasive Wearables Biomonitoring to Detect Pre-Smoking, Smoking, And Post-Smoking Stages), which is not on this map. Cited by 36 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
36citing papers in PubMed, 1 pooled it
2.5field-weighted citation impact, top 11% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT07067151 enrolling by invitationnot on this mapstarted 2026, after this paper: background citation

Use of Noninvasive Wearables Biomonitoring to Detect Pre-Smoking, Smoking, And Post-Smoking Stages: An Observational Laboratory Study

TypeobservationalSponsorNational Institute on Minority Health and Health Disparities (NIMHD)Ran2026 to 2028Enrolled30ConditionsSmoking
3 · Its place in the literature

Who cites it

36 citing papers in PubMed, 1 synthesis or guideline pooled it, 64 citations in OpenAlex.

  1. Pooled it
  2. Detecting Ethanol Intoxication and Impairment Using Wearable Biosensors.Proceedings of the ... Annual Hawaii International Conference on System Sciences. Annual Hawaii International Conference on System Sciences · 2026
    Article
  3. Article
  4. Article
  5. Mobile Health Interventions for Substance Use Disorders.Annual review of clinical psychology · 2024
    Review
  6. Article
  7. Smartphone and Wearable Device-Based Digital Phenotyping to Understand Substance use and its Syndemics.Journal of medical toxicology : official journal of the American College of Medical Toxicology · 2024
    Article
  8. Article
  9. Review
  10. Review
  11. Article
  12. Article
  13. OpiTrack: A Wearable-based Clinical Opioid Use Tracker with Temporal Convolutional Attention Networks.Proceedings of the ACM on interactive, mobile, wearable and ubiquitous technologies · 2021
    Article
  14. Article
  15. Article
  16. Understanding Naloxone Uptake from an Emergency Department Distribution Program Using a Low-Energy Bluetooth Real-time Location System.Journal of medical toxicology : official journal of the American College of Medical Toxicology · 2020
    Observational
  17. Article
  18. Observational
  19. Harmonizing Wearable Biosensor Data Streams to Test Polysubstance Detection.International Conference on Computing, Networking, and Communications : [proceedings]. International Conference on Computing, Networking and Communications · 2020
    Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 1 institution in 1 country.

Stephanie CarreiroDepartment of Emergency Medicine, Division of Medical Toxicology, University of Massachusetts, Worcester, MA, USA.
Hua FangDepartment of Quantitative Health Sciences, University of Massachusetts, 368 Plantation St., Worcester, MA, 01605, USA. HuaJulia.Fang@umassmed.edu.
Jianying ZhangDepartment of Quantitative Health Sciences, University of Massachusetts, 368 Plantation St., Worcester, MA, 01605, USA.
Kelley WittboldDepartment of Emergency Medicine, Division of Medical Toxicology, University of Massachusetts, Worcester, MA, USA.
Shicheng WengDepartment of Quantitative Health Sciences, University of Massachusetts, 368 Plantation St., Worcester, MA, 01605, USA.
Rachel MullinsDepartment of Psychiatry, University of Massachusetts, Worcester, MA, USA.
David SmelsonDepartment of Psychiatry, University of Massachusetts, Worcester, MA, USA.
Edward W BoyerDepartment of Emergency Medicine, Division of Medical Toxicology, University of Massachusetts, Worcester, MA, USA.
University of Massachusetts Chan Medical School · US

Funding

University of Massachusetts Center for Clinical Science and Translational SupplementUL1TR001453 · NCATS · UNIV OF MASSACHUSETTS MED SCH WORCESTER · PI LUZURIAGA, KATHERINE F · 2015 to 2024
$39.0M
University of Massachusetts Center for Clinical and Translational ScienceUL1TR000161 · NCATS · UNIV OF MASSACHUSETTS MED SCH WORCESTER · PI LUZURIAGA, KATHERINE F · 2012 to 2015
$11.0M
Mentoring in Advanced mHealth Technologies and Machine Learning for HIV/Drug Abuse ResearchK24DA037109 · NIDA · UNIV OF MASSACHUSETTS MED SCH WORCESTER · PI BOYER, EDWARD W · 2014 to 2025
$1.9M
iMStrong, an innovative remote monitoring system for detecting cocaine useR01DA033769 · NIDA · UNIV OF MASSACHUSETTS MED SCH WORCESTER · PI BOYER, EDWARD W · 2012 to 2013
$840k
DISC: Describe Smoking Cessation in RCT Multi-Component Behavioral InterventionR01DA033323 · NIDA · UNIV OF MASSACHUSETTS MED SCH WORCESTER · PI FANG, HUA · 2013 to 2015
$701k
NCATS NIH HHS 5UL1TR000161-04NCATS NIH HHS UL1 TR000161NCATS NIH HHS UL1 TR001453NIDA NIH HHS 1R01DA033323-01NIDA NIH HHS K24 DA037109NIDA NIH HHS R01 DA033323NIDA NIH HHS R01 DA033769NIDA NIH HHS R01DA033769-01
6 · The paper itself

Abstract

Biosensor systems are increasingly promoted for use in behavioral interventions. Portable biosensors might offer advancement over self-report use and can provide improved opportunity for detection and intervention in patients undergoing drug treatment programs. Fifteen participants wore a biosensor wristband capable of detecting multiple physiologic markers of sympathetic nervous system (SNS) arousal for 30 days. Urine drug screening and drug use self-report were obtained twice per week. A parameter trajectory description method was applied to capture abrupt changes in magnitude of three measures of SNS activity: Electrodermal activity (EDA), skin temperature and motion. Drug use events detected by the biosensor were verified using a triad of parameters: the biosensor data, urine drug screens, and patient self-report of substance use. Twelve positive cocaine urine screens were identified. Thirteen self-reported episodes of cocaine use were recorded. Distinct episodes with biometric parameters consistent with cocaine use were identified on biosensor data. Eleven potential cocaine use episodes were identified by biosensors that were missed by both self-report and drug screening. Study participants found mobile biosensors to be acceptable, and compliance with the protocol was high. Episodes of cocaine use, as measured by supraphysiologic changes in biophysiometric parameters, were detected by analysis of biosensor data in instances when self-report or drug screening or both failed. Biosensors have substantial potential in detecting substance abuse, in understanding the context of use in real time, and in evaluating the efficacy of behavioral interventions for drug abuse.

Indexed as

AdultCocaineCocaine-Related DisordersFemaleGalvanic Skin ResponseHumansMaleMiddle AgedMonitoring, AmbulatoryMotionReproducibility of ResultsSelf ReportSkin TemperatureSubstance Abuse DetectionCocaineBiosensor systemDrug abusemHealthMobile biosensingParameter trajectory

Identifiers

PMID26490144
PMCPMC4888957
OpenAlexW2133494649

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.