ArticleScientific reports2015
Chromium exposure and incidence of metabolic syndrome among American young adults over a 23-year follow-up: the CARDIA Trace Element Study.
Article in Scientific reports, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers.
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Who cites it
18 citing papers in PubMed, 65 citations in OpenAlex.
- Efficacy and Tolerability of a Food Supplement Based onNutrients · 2024Trial
- Minerals and Human Health: From Deficiency to Toxicity.Nutrients · 2025Review
- Contaminant Metals and Cardiovascular Health.Journal of cardiovascular development and disease · 2023Review
- Article
- Preparation and hypoglycemic effects of chromium- and zinc-richWorld journal of diabetes · 2022Article
- Experimental and Molecular Modeling Studies on the Complexation of Chromium(III) with the Angiotensin-Converting Enzyme Inhibitor Captopril.ACS omega · 2022Article
- Associations Between Serum Multiple Metals Exposures and Metabolic Syndrome: a Longitudinal Cohort Study.Biological trace element research · 2021Article
- Lab-scale evaluation of the microbial bioremediation of Cr(VI): contributions of biosorption, bioreduction, and biomineralization.Environmental science and pollution research international · 2021Article
- Association of plasma chromium with metabolic syndrome among Chinese adults: a case-control study.Nutrition journal · 2020Article
- Article
- Incidence of Metabolic Syndrome in Young Japanese Adults in a 6-Year Cohort Study: The Uguisudani Preventive Health Large-Scale Cohort Study (UPHLS).Journal of epidemiology · 2020Article
- Dietary Patterns and Health Outcomes among African American Maintenance Hemodialysis Patients.Nutrients · 2020Article
- Evaluation of the Effect of Fish Oil Alone and in Combination with a Proprietary Chromium Complex on Endothelial Dysfunction, Systemic Inflammation and Lipid Profile in Type 2 Diabetes Mellitus - A Randomized, Double-Blind, Placebo-Controlled Clinical Study.Diabetes, metabolic syndrome and obesity : targets and therapy · 2020Article
- Toenail Metal Exposures in Fishermen from Bodo City, Nigeria.Bulletin of environmental contamination and toxicology · 2020Article
- Association of urinary metal profiles with serum uric acid: a cross-sectional study of traffic policemen in Wuhan, China.BMJ open · 2019Article
- Localization and Speciation of Chromium in Coptis chinensis Franch. using Synchrotron Radiation X-ray Technology and Laser Ablation ICP-MS.Scientific reports · 2018Article
- Toenail Chromium Concentration and Metabolic Syndrome among Korean Adults.International journal of environmental research and public health · 2018Article
- Inverse Association of Plasma Chromium Levels with Newly Diagnosed Type 2 Diabetes: A Case-Control Study.Nutrients · 2017Article
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Authors and funding
6 authors at 4 institutions in 2 countries.
Funding
Abstract
Studies suggest that chromium deficiency is associated with elevated levels of fasting blood glucose, circulating insulin, cholesterol and triglycerides, and decreased proportion of lean body mass. However, data directly relating chromium levels to metabolic syndrome (MetS) risk are lacking. A total of 3,648 American adults from the Coronary Artery Risk Development in Young Adults (CARDIA) study, aged 20-32 years, were prospectively examined for the incidence of MetS and its five components from 1987-88 to 2010-11. Baseline toenail chromium levels were measured with instrumental neutron-activation analysis. Incident MetS was defined by the NCEP-ATP III criteria. During the 23-year follow-up, 878 incident MetS cases were identified. Baseline toenail chromium was inversely associated with incidence of MetS as well as its blood lipid components. The multivariable-adjusted hazard ratio (HR) (95% confidence interval [CI]) of MetS comparing the highest to the lowest quartiles of toenail chromium levels was 0.80 (0.66-0.98; Plinear trend = 0.006). The adjusted HRs were 0.82 (0.68-0.98; Ptrend = 0.045) for having abnormal triglycerides levels and 0.75 (0.64-0.88; Ptrend = 0.030) for having abnormal HDL cholesterol levels. Toenail chromium levels were inversely and longitudinally associated with incidence of MetS in American young adults. This inverse association was mainly explained by its relation to blood lipids.
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