Evidence map›Paper›PMID 26489026›Full record

ArticleKidney international2015

National outcomes of kidney transplantation from deceased diabetic donors.

Jordana B Cohen, Roy D Bloom, Peter P Reese, Paige M Porrett, Kimberly A Forde, Deirdre L Sawinski

Open access · greenAbstract read
In one paragraph

Article in Kidney international, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 23 papers.

0numbers the graph read from it
0cells of the map it votes in
23citing papers in PubMed
2.3field-weighted citation impact, top 13% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

23 citing papers in PubMed, 35 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Article
  5. Article
  6. Proteinuria in Deceased Diabetic Donors and Kidney Transplant Outcomes.Canadian journal of kidney health and disease · 2026
    Article
  7. Article
  8. Article
  9. Review
  10. Article
  11. Article
  12. Recoverability of Diabetic Nephropathy of Donor Kidney After Kidney Transplantation.Transplant international : official journal of the European Society for Organ Transplantation · 2022
    Article
  13. Deceased Donor Characteristics and Kidney Transplant Outcomes.Transplant international : official journal of the European Society for Organ Transplantation · 2022
    Review
  14. Long-standing donor diabetes and pathologic findings are associated with shorter allograft survival in recipients of kidney transplants from diabetic donors.Modern pathology : an official journal of the United States and Canadian Academy of Pathology, Inc · 2022
    Article
  15. Article
  16. Article
  17. Article
  18. Bariatric surgery before and after kidney transplantation: long-term weight loss and allograft outcomes.Surgery for obesity and related diseases : official journal of the American Society for Bariatric Surgery · 2019
    Article
  19. Article
  20. Inferior long-term allograft and patient outcomes among recipients of offspring living donor kidneys.American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons · 2018
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 1 institution in 1 country.

Jordana B CohenRenal, Electrolyte and Hypertension Division, Department of Medicine, Hospital of the University of Pennsylvania, Philadelphia, Pennsylvania, USA.
Roy D BloomRenal, Electrolyte and Hypertension Division, Department of Medicine, Hospital of the University of Pennsylvania, Philadelphia, Pennsylvania, USA.
Peter P ReeseRenal, Electrolyte and Hypertension Division, Department of Medicine, Hospital of the University of Pennsylvania, Philadelphia, Pennsylvania, USA.
Paige M PorrettDivision of Transplant Surgery, Department of Surgery, Hospital of the University of Pennsylvania, Philadelphia, Pennsylvania, USA.
Kimberly A FordeCenter for Clinical Epidemiology and Biostatistics, Perelman School of Medicine, University of Pennsylvania, Philadelphia, Pennsylvania, USA.
Deirdre L SawinskiRenal, Electrolyte and Hypertension Division, Department of Medicine, Hospital of the University of Pennsylvania, Philadelphia, Pennsylvania, USA.
Hospital of the University of Pennsylvania · US

Funding

CLINICAL RESEARCH TRAINING IN KIDNEY DISEASET32DK007785 · NIDDK · UNIVERSITY OF PENNSYLVANIA · PI FELDMAN, HAROLD I · 2000 to 2019
$3.9M
Obesity, renin-angiotensin-aldosterone blockade, and chronic kidney diseaseF32DK103484 · NIDDK · UNIVERSITY OF PENNSYLVANIA · PI COHEN, JORDANA B. · 2014 to 2015
$145k
NIDDK NIH HHS F32 DK103484NIDDK NIH HHS T32 DK007785
6 · The paper itself

Abstract

Use of deceased diabetic donor kidneys has increased over recent decades. However, scarce patient and allograft survival data are available taking into account recipient diabetes status. Here we performed a retrospective cohort study using data from the United Network of Organ Sharing in patients transplanted from 1994 to 2014. Multivariable Cox regression assessed recipient outcomes of 9074 diabetic vs. 152,555 non-diabetic donor kidneys. Recipients of diabetic donor kidneys had elevated rates of all-cause allograft failure (hazard ratio 1.21, 95% confidence interval 1.16-1.26) and death (1.19, 1.13-1.24) compared to recipients of kidneys from non-diabetic donors. Younger recipients of diabetic donor kidneys had worse allograft survival than older recipients of non-diabetic donor kidneys. There was significant interaction between donor and recipient diabetes status. To minimize the effect of unmeasured confounders, we used paired analyses of recipients of mate-kidneys from the same donor, with one diabetic recipient and the other non-diabetic. Among discordant recipient pairs of diabetic donor kidneys, diabetic recipients had significantly higher risk of allograft failure (1.27, 1.05-1.53) and death (1.53, 1.22-1.93) than non-diabetic recipients. After stratifying by Kidney Donor Profile Index risk category, diabetic recipients of diabetic donor kidneys continued to have worse allograft survival compared to all other patients. Thus, risks are associated with the use of diabetic donor kidneys. Understanding these risks will enable clinicians to better educate potential recipients.Kidney International advance online publication, 21 October 2015; doi:10.1038/ki.2015.325.

Identifiers

PMID26489026
PMCPMC4840104
OpenAlexW2175340913

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.