Evidence map›Paper›PMID 26488871›Full record

ArticlePloS one2015

Incidence of Hospitalized Pneumococcal Pneumonia among Adults in Guatemala, 2008-2012.

Carmen Lucía Contreras, Jennifer R Verani, María Renee Lopez, Antonio Paredes, Chris Bernart, Fabiola Moscoso, Aleida Roldan, Wences Arvelo, Kim A Lindblade, John P McCracken

Open access · goldAbstract read
In one paragraph

Article in PloS one, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.2field-weighted citation impact, top 39% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 4 citations in OpenAlex.

  1. Q Fever as a Cause of Community-Acquired Pneumonia in French Guiana.The American journal of tropical medicine and hygiene · 2022
    Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 3 institutions in 2 countries.

Carmen Lucía ContrerasCenter for Health Studies, Universidad del Valle de Guatemala, Guatemala City, Guatemala.
Jennifer R VeraniNational Center for Immunization and Respiratory Diseases, Centers for Disease Control and Prevention (CDC), Atlanta, GA, United States of America.
María Renee LopezCenter for Health Studies, Universidad del Valle de Guatemala, Guatemala City, Guatemala.
Antonio ParedesNational Center for Epidemiology, Ministry of Public Health and Social Welfare (MSPAS), Guatemala City, Guatemala.
Chris BernartCenter for Health Studies, Universidad del Valle de Guatemala, Guatemala City, Guatemala.
Fabiola MoscosoCenter for Health Studies, Universidad del Valle de Guatemala, Guatemala City, Guatemala.
Aleida RoldanCenter for Health Studies, Universidad del Valle de Guatemala, Guatemala City, Guatemala.
Wences ArveloDivision of Global Disease Detection and Emergency Response, Centers for Disease Control and Prevention (CDC), Atlanta GA, United States of America.
Kim A LindbladeDivision of Global Disease Detection and Emergency Response, Centers for Disease Control and Prevention (CDC), Atlanta GA, United States of America.
John P McCrackenCenter for Health Studies, Universidad del Valle de Guatemala, Guatemala City, Guatemala.
Universidad del Valle de Guatemala · GTCenters for Disease Control and Prevention · USMinistry of Public Health and Social Assistance · GT

Funding

CGH CDC HHS 1U01GH000028CGH CDC HHS U01 GH000028
6 · The paper itself

Abstract

backgroundStreptococcus pneumoniae is a leading cause of pneumonia worldwide. However, the burden of pneumococcal pneumonia among adults in low- and middle-income countries is not well described.

methodsData from 2008-2012 was analyzed from two surveillance sites in Guatemala to describe the incidence of pneumococcal pneumonia in adults. A case of hospitalized pneumococcal pneumonia was defined as a positive pneumococcal urinary antigen test or blood culture in persons aged ≥ 18 years hospitalized with an acute respiratory infection (ARI).

resultsAmong 1595 adults admitted with ARI, 1363 (82%) had either urine testing (n = 1286) or blood culture (n = 338) performed. Of these, 188 (14%) had pneumococcal pneumonia, including 173 detected by urine only, 8 by blood culture only, and 7 by both methods. Incidence rates increased with age, with the lowest rate among 18-24 year-olds (2.75/100,000) and the highest among ≥65 year-olds (31.3/100,000). The adjusted incidence of hospitalized pneumococcal pneumonia was 18.6/100,000 overall, with in-hospital mortality of 5%.

conclusionsAn important burden of hospitalized pneumococcal pneumonia in adults was described, particularly for the elderly. However, even adjusted rates likely underestimate the true burden of pneumococcal pneumonia in the community. These data provide a baseline against which to measure the indirect effects of the 2013 introduction of the pneumococcal conjugate vaccine in children in Guatemala.

Indexed as

Hospital MortalityAdolescentAdultAgedAntigens, BacterialFemaleGuatemalaHospitalizationHumansIncidenceMaleMiddle AgedPneumococcal VaccinesPneumonia, PneumococcalStreptococcus pneumoniaeYoung AdultAntigens, BacterialPneumococcal Vaccines

Identifiers

PMID26488871
PMCPMC4619266
OpenAlexW2140227053

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.