Evidence map›Paper›PMID 26488845›Full record

ArticleEmerging infectious diseases2015

Uncommon Candida Species Fungemia among Cancer Patients, Houston, Texas, USA.

Dong Sik Jung, Dimitrios Farmakiotis, Ying Jiang, Jeffrey J Tarrand, Dimitrios P Kontoyiannis

Open access · diamondAbstract read
In one paragraph

Article in Emerging infectious diseases, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 52 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
52citing papers in PubMed, 1 pooled it
7.4field-weighted citation impact, top 2% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

52 citing papers in PubMed, 1 synthesis or guideline pooled it, 95 citations in OpenAlex.

  1. Pooled it
  2. Clinical Characteristics and Mortality Risk Factors ofAnnals of laboratory medicine · 2026
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  9. Diagnosis and Treatment Challenges ofCase reports in infectious diseases · 2024
    Article
  10. Emergence of cryptic species and clades ofMicrobiology spectrum · 2023
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  13. Article
  14. Review
  15. Article
  16. Microorganisms · 2023
    Review
  17. Article
  18. Review
  19. Infection and drug resistance · 2022
    Review
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 2 countries.

Dong Sik Jung
Dimitrios Farmakiotis
Ying Jiang
Jeffrey J Tarrand
Dimitrios P Kontoyiannis
The University of Texas MD Anderson Cancer Center · USBrown University · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Many uncommon Candida species that cause bloodstream infections (BSIs) are not well-characterized. We investigated the epidemiology, antifungal use, susceptibility patterns, and factors associated with all-cause death among cancer patients in whom uncommon Candida spp. BSIs were diagnosed at a cancer treatment center during January 1998–September 2013. Of 1,395 Candida bloodstream isolates, 79 from 68 patients were uncommon Candida spp. The incidence density of uncommon Candida spp. BSIs and their proportion to all candidemia episodes substantively increased during the study period, and the rise was associated with increasing use of echinocandin antifungal drugs. Thirty-seven patients had breakthrough infections during therapy or prophylaxis with various systemic antifungal drugs for >7 consecutive days; 21 were receiving an echinocandin. C. kefyr (82%), and C. lusitaniae (21%) isolates frequently showed caspofungin MICs above the epidemiologic cutoff values. These findings support the need for institutional surveillance for uncommon Candida spp. among cancer patients.

Indexed as

Antifungal AgentsCandidaCandidemiaCandidiasisCulture MediaEducation, Medical, ContinuingHumansIncidenceMicrobial Sensitivity TestsNeoplasmsRisk FactorsTexasAntifungal AgentsCulture Mediaantimicrobial drugscancerCandidacandidemiacaspofunginC. dublinensisC. famataC. guilliermondiiC. kefyrC. lusitaniaeechinocandinsfungiHoustonnon-albicansTexasUSA

Identifiers

PMID26488845
PMCPMC4625381
OpenAlexW1777846564

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.