Evidence map›Paper›PMID 26488485›Full record

ArticleEmerging infectious diseases2015

Fosfomycin Resistance in Escherichia coli, Pennsylvania, USA.

Hind Alrowais, Christi L McElheny, Caressa N Spychala, Sangeeta Sastry, Qinglan Guo, Adeel A Butt, Yohei Doi

Open access · diamondAbstract read
In one paragraph

Article in Emerging infectious diseases, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 27 papers.

0numbers the graph read from it
0cells of the map it votes in
27citing papers in PubMed
2.3field-weighted citation impact, top 12% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

27 citing papers in PubMed, 54 citations in OpenAlex.

  1. Article
  2. Observational
  3. Review
  4. Antibiotics (Basel, Switzerland) · 2025
    Article
  5. Article
  6. Review
  7. Emergence of Fosfomycin Resistance by Plasmid-MediatedAntibiotics (Basel, Switzerland) · 2022
    Article
  8. Article
  9. Global Threat of Carbapenem-Resistant Gram-Negative Bacteria.Frontiers in cellular and infection microbiology · 2022
    Review
  10. Article
  11. Article
  12. Article
  13. Prevalence of fosfomycin resistance among ESBL-producing Escherichia coli isolates in the community, Switzerland.European journal of clinical microbiology & infectious diseases : official publication of the European Society of Clinical Microbiology · 2019
    Article
  14. Fosfomycin in infections caused by multidrug-resistant Gram-negative pathogens.Revista espanola de quimioterapia : publicacion oficial de la Sociedad Espanola de Quimioterapia · 2019
    Review
  15. Article
  16. Origin of the plasmid-mediated fosfomycin resistance gene fosA3.The Journal of antimicrobial chemotherapy · 2018
    Article
  17. ESBL-producingFood safety (Tokyo, Japan) · 2017
    Review
  18. Article
  19. Article
  20. First Detection of a Fosfomycin Resistance Gene,Antimicrobial agents and chemotherapy · 2017
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 2 institutions in 2 countries.

Hind Alrowais
Christi L McElheny
Caressa N Spychala
Sangeeta Sastry
Qinglan Guo
Adeel A Butt
Yohei Doi
Fudan University · CNUniversity of Pittsburgh · US

Funding

Colistin-resistant Acinetobacter baumanniiR01AI104895 · NIAID · UNIVERSITY OF PITTSBURGH AT PITTSBURGH · PI DOI, YOHEI, ERNST, ROBERT K · 2014 to 2024
$4.2M
Markers predicting response to therapy for KPC-producing Klebsiella pneumoniaeR21AI107302 · NIAID · UNIVERSITY OF PITTSBURGH AT PITTSBURGH · PI DOI, YOHEI · 2013 to 2014
$409k
NIAID NIH HHS R01 AI104895NIAID NIH HHS R01AI104895NIAID NIH HHS R21 AI107302NIAID NIH HHS R21AI107302
6 · The paper itself

Abstract

Fosfomycin resistance in Escherichia coli is rare in the United States. An extended-spectrum β-lactamase-producing E. coli clinical strain identified in Pennsylvania, USA, showed high-level fosfomycin resistance caused by the fosA3 gene. The IncFII plasmid carrying this gene had a structure similar to those found in China, where fosfomycin resistance is commonly described.

Indexed as

Anti-Bacterial AgentsDrug Resistance, BacterialEscherichia coliEscherichia coli InfectionsFemaleFosfomycinHumansPennsylvaniaSequence Analysis, DNAAnti-Bacterial AgentsFosfomycin16S rRNA methyltransferaseantimicrobial resistancebacteriaESBLEscherichia coliextended-spectrum β-lactamasefosA3 genefosfomycin resistanceglutathione S-transferasePennsylvaniaplasmidsUnited States

Identifiers

PMID26488485
PMCPMC4622254
OpenAlexW2180534302

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.