ReviewAnimals : an open access journal from MDPI2013
Ethnopharmacological Survey of Plants Used in the Traditional Treatment of Gastrointestinal Pain, Inflammation and Diarrhea in Africa: Future Perspectives for Integration into Modern Medicine.
Review in Animals : an open access journal from MDPI, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
18 citing papers in PubMed.
- Erucastrum virgatum subsp. virgatum (Brassicaceae) Endemic to Sicily (Italy): Biological Properties and Phenolic Content of Leaf Extracts.Chemistry & biodiversity · 2026Article
- Morpho-biochemical diversity and phytochemical profiling of Rubus fruticosus L. landraces.PloS one · 2026Article
- Bioactive Molecules, Ethnomedicinal Uses, Toxicology, and Pharmacology ofPlants (Basel, Switzerland) · 2025Review
- A Comprehensive Review of Ethnomedicinal Uses, Phytochemistry, Pharmacology, and Toxicity ofScientifica · 2024Review
- Editorial: Treatment of animal diseases with veterinary phytotherapy.Frontiers in veterinary science · 2023Article
- Ethnomedicinal uses, phytochemistry, and pharmacology of the genusFrontiers in pharmacology · 2023Review
- Sub-acute toxicity study on hydromethanolic leaves extract ofToxicological research · 2022Article
- Preclinical Pharmacokinetic and Pharmacodynamic Investigation of 5'-Methoxynobiletin from Ageratum conyzoides: In vivo and In silico Approaches.Pharmaceutical research · 2022Article
- Treatment of Benign Prostatic Hyperplasia by Natural Drugs.Molecules (Basel, Switzerland) · 2021Review
- Ethnobotany, Ethnopharmacology, and Phytochemistry of Medicinal Plants Used for Treating Human Diarrheal Cases in Rwanda: A Review.Antibiotics (Basel, Switzerland) · 2021Review
- (9βH)- and 17-Nor-Pimaranes fromJournal of natural products · 2021Article
- Medicinal Plants for Mitigating Pain and Inflammatory-Related Conditions: An Appraisal of Ethnobotanical Uses and Patterns in South Africa.Frontiers in pharmacology · 2021Article
- Evaluation of Anti-Diarrheal Activity of 80% Methanol Extracts ofJournal of experimental pharmacology · 2020Article
- Eugenol prevents fMLF-induced superoxide anion production in human neutrophils by inhibiting ERK1/2 signaling pathway and p47phox phosphorylation.Scientific reports · 2019Article
- Antifungal, anti-oxidant activity and cytotoxicity of South African medicinal plants against mycotoxigenic fungi.Heliyon · 2018Article
- Phytochemical analysis, antioxidant and anti-inflammatory potential of FERETIA APODANTHERA root bark extracts.BMC complementary and alternative medicine · 2018Article
- Anvillea garcinii extract inhibits the oxidative burst of primary human neutrophils.BMC complementary and alternative medicine · 2016Article
- Review of the Phytochemical and Pharmacological Studies of the Genus Markhamia.Pharmacognosy reviewsArticle
Corrections and comments
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Authors and funding
3 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
There is a growing need to find the most appropriate and effective treatment options for a variety of painful syndromes, including conditions affecting the gastrointestinal tract, for treating both veterinary and human patients. The most successful regimen may come through integrated therapies including combining current and novel western drugs with acupuncture and botanical therapies or their derivatives. There is an extensive history and use of plants in African traditional medicine. In this review, we have highlighted botanical remedies used for treatment of pain, diarrheas and inflammation in traditional veterinary and human health care in Africa. These preparations are promising sources of new compounds comprised of flavonoids, bioflavanones, xanthones, terpenoids, sterols and glycosides as well as compound formulas and supplements for future use in multimodal treatment approaches to chronic pain, gastrointestinal disorders and inflammation. The advancement of plant therapies and their derivative compounds will require the identification and validation of compounds having specific anti-nociceptive neuromodulatory and/or anti-inflammatory effects. In particular, there is need for the identification of the presence of compounds that affect purinergic, GABA, glutamate, TRP, opioid and cannabinoid receptors, serotonergic and chloride channel systems through bioactivity-guided, high-throughput screening and biotesting. This will create new frontiers for obtaining novel compounds and herbal supplements to relieve pain and gastrointestinal disorders, and suppress inflammation.
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Registered trials
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