Evidence map›Paper›PMID 26487300›Full record

Trial reportAIDS and behavior2016

Randomized Controlled Trial of an Internet Application to Reduce HIV Transmission Behavior Among HIV Infected Men Who have Sex with Men.

Joel Milam, Sheldon Morris, Sonia Jain, Xiaoying Sun, Michael P Dubé, Eric S Daar, Gustavo Jimenez, Richard Haubrich, CCTG 592 Team

Abstract readRandomized Controlled Trial
PubMed Full text at PMC Publisher
In one paragraph

Trial report in AIDS and behavior, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers, 8 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
16citing papers in PubMed, 8 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

16 citing papers in PubMed, 8 syntheses or guidelines pooled it.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Joel Milam *Keck School of Medicine, University of Southern California, 2001 Soto Building, MC9239, Los Angeles, CA 90032, USA.
Sheldon Morris *University of California, San Diego, CA, USA.
Sonia JainUniversity of California, San Diego, CA, USA.
Xiaoying SunUniversity of California, San Diego, CA, USA.
Michael P DubéKeck School of Medicine, University of Southern California, 2001 Soto Building, MC9239, Los Angeles, CA 90032, USA.
Eric S DaarLos Angeles Biomedical Research Institute at Harbor-UCLA Medical Center, Long Beach, CA, USA.
Gustavo JimenezUniversity of California, San Diego, CA, USA.
Richard HaubrichUniversity of California, San Diego, CA, USA.
CCTG 592 Team

Funding

VirologyP30AI036214 · NIAID · UNIVERSITY OF CALIFORNIA, SAN DIEGO · PI David Mitchell Smith · 1994 to 2026
$78.4M
Improving Antiretroviral Management for HIVK24AI064086 · NIAID · UNIVERSITY OF CALIFORNIA, SAN DIEGO · PI HAUBRICH, RICHARD H · 2006 to 2015
$1.8M
NIAID NIH HHS K24 AI064086NIAID NIH HHS P30 AI036214
6 · The paper itself

Abstract

We conducted a prospective, randomized controlled trial of an internet-based safer-sex intervention to reduce HIV transmission risk behaviors. HIV-infected men who have sex with men (n = 179) were randomized to receive a monthly internet survey alone or a monthly survey plus tailored risk reduction messages over 12 months. The primary outcome was the cumulative sexually transmitted infection (STI) incidence over 12 months. Secondary outcomes included self-reported unprotected sex with an at risk partner and disclosure of HIV status to partners. In a modified intent to treat analysis, there was no difference in 12-month STI incidence between the intervention and control arms (30 vs. 25 %, respectively; p = 0.5). Unprotected sex decreased and disclosure increased over time in both study arms. These improvements suggest that addition of the risk-reduction messages provided little benefit beyond the self-monitoring of risky behavior via regular self-report risk behavior assessments (as was done in both study arms).

Indexed as

Homosexuality, MaleInternetAdultHealth Knowledge, Attitudes, PracticeHIV InfectionsHumansIncidenceMaleMiddle AgedProspective StudiesRisk Reduction BehaviorRisk-TakingSafe SexSelf ReportSexually Transmitted DiseasesSexual PartnersHIVInternetInterventionMen who have sex with menRandomized controlled trialRisk behaviorsSexually transmitted infection

Identifiers

PMID26487300
PMCPMC4838553

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.