Evidence map›Paper›PMID 26487298›Full record

ArticleAIDS and behavior2016

Factors Associated with Prescription of Opioids and Co-prescription of Sedating Medications in Individuals with HIV.

Jessica S Merlin, Ashutosh Tamhane, Joanna L Starrels, Stefan Kertesz, Michael Saag, Karen Cropsey

Registry-linked trialOpen access · greenAbstract read
In one paragraph

Article in AIDS and behavior, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT03692611 (Evaluation of the Efficacy and Mechanisms of a Novel Intervention for Chronic Pain Tailored to People Living With HIV), which is not on this map. Cited by 23 papers.

0numbers the graph read from it
0cells of the map it votes in
23citing papers in PubMed
2.0field-weighted citation impact, top 13% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT03692611 nacompletednot on this mapstarted 2019, after this paper: background citation

Evaluation of the Efficacy and Mechanisms of a Novel Intervention for Chronic Pain Tailored to People Living With HIV

TypeinterventionalSponsorUniversity of PittsburghRan2019 to 2025Enrolled278ConditionsChronic PainArmsSkills TO Manage Pain (STOMP), Comparison group
3 · Its place in the literature

Who cites it

23 citing papers in PubMed, 30 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 3 institutions in 1 country.

Jessica S MerlinDivision of Infectious Diseases, Department of Medicine, University of Alabama at Birmingham, BBRB 222, 1530 3rd Ave S, Birmingham, AL, 35294-2170, USA. jmerlin@uab.edu.
Ashutosh TamhaneDivision of Infectious Diseases, Department of Medicine, University of Alabama at Birmingham, BBRB 222, 1530 3rd Ave S, Birmingham, AL, 35294-2170, USA.
Joanna L StarrelsDepartment of Medicine, Albert Einstein College of Medicine, Bronx, NY, USA.
Stefan KerteszBirmingham VA Medical Center, Birmingham, AL, USA.
Michael SaagDivision of Infectious Diseases, Department of Medicine, University of Alabama at Birmingham, BBRB 222, 1530 3rd Ave S, Birmingham, AL, 35294-2170, USA.
Karen CropseyDepartment of Psychiatry, University of Alabama at Birmingham, Birmingham, AL, USA.
University of Alabama at Birmingham · USAlbert Einstein College of Medicine · USBirmingham VA Medical Center · US

Funding

Virology CoreP30AI027767 · NIAID · UNIVERSITY OF ALABAMA AT BIRMINGHAM · PI OLAF KUTSCH · 1988 to 2026
$84.1M
Prescription opioid use, misuse, disorders and HIV outcomesR01DA039046 · NIDA · ALBERT EINSTEIN COLLEGE OF MEDICINE, INC · PI STARRELS, JOANNA L. · 2015 to 2018
$2.4M
Intervention to Promote Opioid Treatment Agreements in Primary CareK23DA027719 · NIDA · ALBERT EINSTEIN COLLEGE OF MEDICINE, INC · PI STARRELS, JOANNA L. · 2010 to 2014
$909k
Development of a Behavioral Intervention for Chronic Pain in Individuals with HIVK23MH104073 · NIMH · UNIVERSITY OF PITTSBURGH AT PITTSBURGH · PI MERLIN, JESSICA S · 2015 to 2018
$732k
NIAID NIH HHS P30 AI027767NIDA NIH HHS K23 DA027719NIDA NIH HHS R01 DA039046NIMH NIH HHS K23 MH104073PHS HHS P30 A1027767
6 · The paper itself

Abstract

Opioids are often prescribed for chronic pain, and opioid risks such as overdose and death are heightened when opioids are co-prescribed with other sedating medications. We investigated factors associated with chronic opioid prescription, alone and in combination with benzodiazepines and muscle relaxants, in a clinical cohort of individuals with HIV. We used multivariable logistic regression models to determine participant clinical and demographic characteristics that are associated with chronic prescription of opioids or chronic co-prescription of opioids with sedating medications. Among 1474 participants, chronic prescription of opioids occurred in 253 individuals (17.2 %), and chronic co-prescription occurred in 90 individuals (6.1 %). Age >50, public insurance as compared to private insurance, and symptoms of depression and anxiety were significantly associated with chronic opioid prescription and chronic co-prescription. Our findings raise concern that opioid prescription and co-prescription of sedating medications occurs disproportionately in patients for whom use is riskier.

Indexed as

AdultAgedAnalgesics, OpioidAnxietyBenzodiazepinesChronic PainCohort StudiesCross-Sectional StudiesDepressionDrug PrescriptionsFemaleHIV InfectionsHumansLogistic ModelsMaleMiddle AgedAnalgesics, OpioidBenzodiazepinesMuscle Relaxants, CentralBenzodiazepineChronic painHIVMuscle relaxantOpioid

Identifiers

PMID26487298
PMCPMC4777647
OpenAlexW2162998753

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.