ArticleBMC cancer2015
Endometriosis as a risk factor for ovarian or endometrial cancer - results of a hospital-based case-control study.
Article in BMC cancer, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers, 1 of them a synthesis that pooled it.
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Who cites it
16 citing papers in PubMed, 1 synthesis or guideline pooled it.
- The association between endometriosis and risk of endometrial cancer and breast cancer: a meta-analysis.BMC women's health · 2022Pooled it
- Endometriosis and endometrial cancer: A propensity score-adjusted real-world data study.iScience · 2024Article
- Primary vaginal cancer after hysterectomy for benign conditions: a systematic review of the literature.Frontiers in oncology · 2024Review
- Epidemiological trends and risk factors of gynecological cancers: an update.Medical oncology (Northwood, London, England) · 2023Review
- History of Endometriosis Is Independently Associated with an Increased Risk of Ovarian Cancer.Journal of personalized medicine · 2022Article
- The multistep process of vaginal cancer arising from deep infiltrating endometriosis: a case report.BMC women's health · 2021Article
- Long-term Health Consequences of Endometriosis - Pathways and Mediation by Treatment.Current obstetrics and gynecology reports · 2020Article
- Malignant Transformation and Associated Biomarkers of Ovarian Endometriosis: A Narrative Review.Advances in therapy · 2020Review
- Association between endometriosis and gynecological cancers: a critical review of the literature.Archives of gynecology and obstetrics · 2020Review
- Subsequent Development of Epithelial Ovarian Cancer After Ovarian Surgery for Benign Ovarian Tumor: A Population-Based Cohort Study.Clinical epidemiology · 2020Article
- Risk of postmenopausal hormone therapy and patient history factors for the survival rate in women with endometrial carcinoma.Archives of gynecology and obstetrics · 2020Article
- Angiogenesis in Gynecological Cancers: Role of Neurotrophins.Frontiers in oncology · 2019Review
- Review
- Endometriosis and endometriosis-associated cancers: new insights into the molecular mechanisms of ovarian cancer development.Ecancermedicalscience · 2018Review
- Common Dysregulated Genes in Endometriosis and Malignancies.Revista brasileira de ginecologia e obstetricia : revista da Federacao Brasileira das Sociedades de Ginecologia e Obstetricia · 2016Review
- Simultaneous Endometrial Cancer with Extensive Pelvic and Vulvar Endometriosis: A Case Report.Journal of reproduction & infertilityArticle
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13 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundNo screening programs are available for ovarian or endometrial cancer. One reason for this is the low incidence of the conditions, resulting in low positive predictive values for tests, which are not very specific. One way of addressing this problem might be to use risk factors to define subpopulations with a higher incidence. The aim of this study was to investigate the extent to which a medical history of endometriosis can serve as a risk factor for ovarian or endometrial cancer.
methodsIn a hospital-based case-control analysis, the cases represented patients with endometrial or ovarian cancer who were participating in studies aimed at assessing the risk for these diseases. The controls were women between the age of 40 and 85 who were invited to take part via a newspaper advertisement. A total of 289 cases and 1016 controls were included. Using logistic regression models, it was tested whether self-reported endometriosis is a predictor of case-control status in addition to age, body mass index (BMI), number of pregnancies and previous oral contraceptive (OC) use.
resultsEndometriosis was reported in 2.1 % of the controls (n = 21) and 4.8 % of the cases (n = 14). Endometriosis was a relevant predictor for case-control status in addition to other predictive factors (OR 2.63; 95 % CI, 1.28 to 5.41).
conclusionThis case-control study found that self-reported endometriosis may be a risk factor for endometrial or ovarian cancer in women between 40 and 85 years. There have been very few studies addressing this issue, and incorporating it into a clinical prediction model would require a more precise characterization of the risk factor of endometriosis.
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