ArticleScientific reports2015
A proteomic analysis of seeds from Bt-transgenic Brassica napus and hybrids with wild B. juncea.
Article in Scientific reports, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.
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12 citing papers in PubMed, 22 citations in OpenAlex.
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- Effects of stacking breeding on the methylome and transcriptome profile of transgenic rice with glyphosate tolerance.Planta · 2023Article
- Analysis of Altered Flowering Related Genes in a Multi-Silique Rapeseed (Plants (Basel, Switzerland) · 2023Article
- Proteomic Analysis ofPlants (Basel, Switzerland) · 2023Article
- Proteomic and Metabolomic Evaluation of Insect- and Herbicide-Resistant Maize Seeds.Metabolites · 2022Article
- Integrated proteomics and metabolomics analysis of transgenic and gene-stacked maize line seeds.GM crops & food · 2021Article
- Untargeted Proteomics-Based Approach to Investigate Unintended Changes in Genetically Modified Maize for Environmental Risk Assessment Purpose.Frontiers in toxicology · 2021Article
- Exogenous Cry1Ab/c Protein Recruits Different Endogenous Proteins for Its Function in Plant Growth and Development.Frontiers in bioengineering and biotechnology · 2020Article
- Article
- Genetic variation assessment of stacked-trait transgenic maize via conventional breeding.BMC plant biology · 2019Article
- iTRAQ-based quantitative tissue proteomic analysis of differentially expressed proteins (DEPs) in non-transgenic and transgenic soybean seeds.Scientific reports · 2018Article
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Authors and funding
8 authors at 4 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Transgene insertions might have unintended side effects on the transgenic host, both crop and hybrids with wild relatives that harbor transgenes. We employed proteomic approaches to assess protein abundance changes in seeds from Bt-transgenic oilseed rape (Brassica napus) and its hybrids with wild mustard (B. juncea). A total of 24, 15 and 34 protein spots matching to 23, 13 and 31 unique genes were identified that changed at least 1.5 fold (p < 0.05, Student's t-test) in abundance between transgenic (tBN) and non-transgenic (BN) oilseed rape, between hybrids of B. juncea (BJ) × tBN (BJtBN) and BJ × BN (BJBN) and between BJBN and BJ, respectively. Eight proteins had higher abundance in tBN than in BN. None of these proteins was toxic or nutritionally harmful to human health, which is not surprising since the seeds are not known to produce toxic proteins. Protein spots varying in abundance between BJtBN and BJBN seeds were the same or homologous to those in the respective parents. None of the differentially-accumulated proteins between BJtBN and BJBN were identical to those between tBN and BN. Results indicated that unintended effects resulted from transgene flow fell within the range of natural variability of hybridization and those found in the native host proteomes.
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