Evidence map›Paper›PMID 26486595›Full record

ArticleBMC gastroenterology2015

Gastric cancer diagnosed after Helicobacter pylori eradication in diabetes mellitus patients.

Kosuke Sakitani, Yoshihiro Hirata, Nobumi Suzuki, Satoki Shichijo, Ayako Yanai, Takako Serizawa, Kei Sakamoto, Masao Akanuma, Shin Maeda, Yutaka Yamaji and 3 more

Open access · goldAbstract read
In one paragraph

Article in BMC gastroenterology, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers, 3 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed, 3 pooled it
1.8field-weighted citation impact, top 15% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 3 syntheses or guidelines pooled it, 16 citations in OpenAlex.

  1. Pooled it
  2. Pooled it
  3. Pooled it
  4. [Clinical Application of the Kyoto Classification of Gastritis].The Korean journal of helicobacter and upper gastrointestinal research · 2023
    Review
  5. Article
  6. Endoscopic Kyoto classification ofWorld journal of gastroenterology · 2020
    Review
  7. Review
  8. Article
  9. Characteristics and predictors of gastric cancer afterWorld journal of gastroenterology · 2018
    Review
  10. Article
  11. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors at 4 institutions in 1 country.

Kosuke SakitaniThe Institute for Adult Diseases, Asahi Life Foundation, 2-2-6 Bakuro-cho, Nihon-Bashi, Chuo-ku, Tokyo, 113-8655, Japan. sakitani-tky@umin.ac.jp.
Yoshihiro HirataDepartment of Gastroenterology, Graduate School of Medicine, The University of Tokyo, Tokyo, Japan. hiratay-int@h.u-tokyo.ac.jp.
Nobumi SuzukiThe Institute for Adult Diseases, Asahi Life Foundation, 2-2-6 Bakuro-cho, Nihon-Bashi, Chuo-ku, Tokyo, 113-8655, Japan. nobu3szk@yahoo.co.jp.
Satoki ShichijoDepartment of Gastroenterology, Graduate School of Medicine, The University of Tokyo, Tokyo, Japan. 7satoki@gmail.com.
Ayako YanaiThe Institute for Adult Diseases, Asahi Life Foundation, 2-2-6 Bakuro-cho, Nihon-Bashi, Chuo-ku, Tokyo, 113-8655, Japan. ayanai-gi@umin.ac.jp.
Takako SerizawaDepartment of Gastroenterology, Graduate School of Medicine, The University of Tokyo, Tokyo, Japan. st8039-fki@umin.ac.jp.
Kei SakamotoThe Institute for Adult Diseases, Asahi Life Foundation, 2-2-6 Bakuro-cho, Nihon-Bashi, Chuo-ku, Tokyo, 113-8655, Japan. ksakamoto.spvir@gmail.com.
Masao AkanumaThe Institute for Adult Diseases, Asahi Life Foundation, 2-2-6 Bakuro-cho, Nihon-Bashi, Chuo-ku, Tokyo, 113-8655, Japan. m-akanuma@asahi-life.or.jp.
Shin MaedaGastroenterology Division, Yokohama City University Graduate School of Medicine, Yokohama, Japan. smaeda@yokohama-cu.ac.jp.
Yutaka YamajiDepartment of Gastroenterology, Graduate School of Medicine, The University of Tokyo, Tokyo, Japan. yamaji-tky@umin.ac.jp.
Yasuhiko IwamotoThe Institute for Adult Diseases, Asahi Life Foundation, 2-2-6 Bakuro-cho, Nihon-Bashi, Chuo-ku, Tokyo, 113-8655, Japan. y-iwamoto@asahi-life.or.jp.
Shoji KawazuThe Institute for Adult Diseases, Asahi Life Foundation, 2-2-6 Bakuro-cho, Nihon-Bashi, Chuo-ku, Tokyo, 113-8655, Japan. skawa@asahi-life.or.jp.
Kazuhiko KoikeDepartment of Gastroenterology, Graduate School of Medicine, The University of Tokyo, Tokyo, Japan. kkoike-tky@umin.ac.jp.
The Institute of Medical Science, Asahi Life Foundation · JPThe University of Tokyo · JPUniversity of Tokyo Hospital · JPYokohama City University · JP

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundHelicobacter pylori infection is the most important risk factor for gastric cancer, for which eradication therapy is commonly performed. However, gastric cancer is sometimes discovered after successful eradication of H. pylori. Much evidence indicates that diabetes mellitus (DM) is a risk factor for gastric cancer. The incidence and characteristics of gastric cancer diagnosed after H. pylori eradication in DM patients remain to be determined.

methodsWe followed the clinical course of patients who underwent H. pylori eradication therapy at our institution. Endoscopy was performed before and after eradication. We compared the incidence and clinical characteristics of gastric cancer arising in DM and non-DM patients.

resultsIn total, 965 patients who underwent successful eradication (518 DM and 447 non-DM patients) were followed-up for an average of 4.5 years. During the follow-up period, 21 gastric cancers were diagnosed (12 in DM patients and 9 in non-DM patients). The incidence of gastric cancer after eradication was not significantly different between DM and non-DM patients (0.485 and 0.482 %/year, respectively). There was no significant difference in the pathology, diameter, depth, location, or treatment of gastric cancer between patients with and without DM.

conclusionThe incidence and characteristics of gastric cancer occurring after H. pylori eradication were comparable between DM and non-DM patients.

Indexed as

Helicobacter pyloriAdultAgedAged, 80 and overAnti-Bacterial AgentsDiabetes ComplicationsDiabetes MellitusFemaleFollow-Up StudiesHelicobacter InfectionsHumansIncidenceMaleMiddle AgedRisk FactorsStomach NeoplasmsAnti-Bacterial Agents

Identifiers

PMID26486595
PMCPMC4617907
OpenAlexW2179876353

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.