ArticleEuropean journal of human genetics : EJHG2016
Genetic evidence for an origin of the Armenians from Bronze Age mixing of multiple populations.
Article in European journal of human genetics : EJHG, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 24 papers.
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Who cites it
24 citing papers in PubMed.
- Palaeoproteomic and genetic insights into millennial-scale dairy consumption in Armenia.iScience · 2026Article
- Article
- Demographic history and genetic variation of the Armenian population.American journal of human genetics · 2025Article
- Development of biobanking infrastructure in Armenia: opportunities and challenges.Frontiers in public health · 2025Review
- Genetic Analysis of Mingrelians Reveals Long-Term Continuity of Populations in Western Georgia (Caucasus).Genome biology and evolution · 2023Article
- PTPN22 intron polymorphism rs1310182 (c.2054-852T>C) is associated with type 1 diabetes mellitus in patients of Armenian descent.PloS one · 2023Article
- Impact of cultural and genetic structure on food choices along the Silk Road.Proceedings of the National Academy of Sciences of the United States of America · 2022Article
- Multivariate statistical approach and machine learning for the evaluation of biogeographical ancestry inference in the forensic field.Scientific reports · 2022Article
- Variation of Genomic Sites Associated with Severe Covid-19 Across Populations: Global and National Patterns.Pharmacogenomics and personalized medicine · 2021Article
- Comparative Y-chromosome analysis among Cypriots in the context of historical events and migrations.PloS one · 2021Article
- Article
- Genetic Diversity and Low Stratification of the Population of the United Arab Emirates.Frontiers in genetics · 2020Article
- Insights into matrilineal genetic structure, differentiation and ancestry of Armenians based on complete mitogenome data.Molecular genetics and genomics : MGG · 2019Article
- Y-chromosome and Surname Analyses for Reconstructing Past Population Structures: The Sardinian Population as a Test Case.International journal of molecular sciences · 2019Article
- Distinct genetic variation and heterogeneity of the Iranian population.PLoS genetics · 2019Article
- A Transient Pulse of Genetic Admixture from the Crusaders in the Near East Identified from Ancient Genome Sequences.American journal of human genetics · 2019Article
- Population Levels Assessment of the Distribution of Disease-Associated Variants With Emphasis on Armenians - A Machine Learning Approach.Frontiers in genetics · 2019Article
- Involvement of polymorphisms of the nerve growth factor and its receptor encoding genes in the etiopathogenesis of ischemic stroke.BMC medical genetics · 2018Article
- Between Lake Baikal and the Baltic Sea: genomic history of the gateway to Europe.BMC genetics · 2017Article
- Genetic and linguistic histories in Central Asia inferred using approximate Bayesian computations.Proceedings. Biological sciences · 2017Article
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7 authors.
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Abstract
The Armenians are a culturally isolated population who historically inhabited a region in the Near East bounded by the Mediterranean and Black seas and the Caucasus, but remain under-represented in genetic studies and have a complex history including a major geographic displacement during World War I. Here, we analyse genome-wide variation in 173 Armenians and compare them with 78 other worldwide populations. We find that Armenians form a distinctive cluster linking the Near East, Europe, and the Caucasus. We show that Armenian diversity can be explained by several mixtures of Eurasian populations that occurred between ~3000 and ~2000 bce, a period characterized by major population migrations after the domestication of the horse, appearance of chariots, and the rise of advanced civilizations in the Near East. However, genetic signals of population mixture cease after ~1200 bce when Bronze Age civilizations in the Eastern Mediterranean world suddenly and violently collapsed. Armenians have since remained isolated and genetic structure within the population developed ~500 years ago when Armenia was divided between the Ottomans and the Safavid Empire in Iran. Finally, we show that Armenians have higher genetic affinity to Neolithic Europeans than other present-day Near Easterners, and that 29% of Armenian ancestry may originate from an ancestral population that is best represented by Neolithic Europeans.
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