ArticleJournal of community hospital internal medicine perspectives2015
Spontaneous complete remission of type 1 diabetes mellitus in an adult - review and case report.
Article in Journal of community hospital internal medicine perspectives, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers, 1 of them a synthesis that pooled it.
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Who cites it
15 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Autoimmune diabetes mellitus after COVID-19 vaccination in adult population: a systematic review of case reports.BMC endocrine disorders · 2023Pooled it
- Role of EP4 factor in paediatric type 1 diabetes mellitus: a comprehensive review focusing on the honeymoon period.Pediatric endocrinology, diabetes, and metabolism · 2024Review
- Association between sitagliptin plus vitamin D3 (VIDPP-4i) use and clinical remission in patients with new-onset type 1 diabetes: a retrospective case-control study.Archives of endocrinology and metabolism · 2023Article
- Six-Year Complete Remission of Type-1 Diabetes Mellitus in an Adult Treated With Sitagliptin.Cureus · 2023Article
- Article
- Trajectories in HbA1c and other risk factors among adults with type 1 diabetes by age at onset.BMJ open diabetes research & care · 2021Article
- C-peptide and residual β-cell function in pediatric diabetes - state of the art.Pediatric endocrinology, diabetes, and metabolism · 2021Review
- Prolonged Honeymoon Period in a Thai Patient with Adult-Onset Type 1 Diabetes Mellitus.Case reports in endocrinology · 2021Article
- Influence of Age on Partial Clinical Remission among Children with Newly Diagnosed Type 1 Diabetes.International journal of environmental research and public health · 2020Article
- Insulin Independence in Newly Diagnosed Type 1 Diabetes Patient following Fenofibrate Treatment.Case reports in medicine · 2020Article
- Atypical hyperglycemia presentation suggests considering a diagnostic of other types of diabetes: first reported GCK-MODY in Perú.Clinical diabetes and endocrinology · 2020Article
- Scanning X-ray microdiffraction of decellularized pericardium tissue at increasing glucose concentration.Journal of biophotonics · 2019Article
- Active Subjects With Autoimmune Type 1 Diabetes Have Better Metabolic Profiles Than Sedentary Controls.Cell transplantation · 2017Article
- Combined treatment with sitagliptin and vitamin D in a patient with latent autoimmune diabetes in adults.Endocrinology, diabetes & metabolism case reports · 2016Article
- Rapid assessment of health literacy on admission to the hospital.Journal of community hospital internal medicine perspectives · 2015Article
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Authors and funding
8 authors.
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No grant is acknowledged in the PubMed record.
Abstract
Type 1 diabetes mellitus (T1DM) is an autoimmune condition that results in low plasma insulin levels by destruction of beta cells of the pancreas. As part of the natural progression of this disease, some patients regain beta cell activity transiently. This period is often referred to as the 'honeymoon period' or remission of T1DM. During this period, patients manifest improved glycemic control with reduced or no use of insulin or anti-diabetic medications. The incidence rates of remission and duration of remission is extremely variable. Various factors seem to influence the remission rates and duration. These include but are not limited to C-peptide level, serum bicarbonate level at the time of diagnosis, duration of T1DM symptoms, haemoglobin A1C (HbA1C) levels at the time of diagnosis, sex, and age of the patient. Mechanism of remission is not clearly understood. Extensive research is ongoing in regard to the possible prevention and reversal of T1DM. However, most of the studies that showed positive results were small and uncontrolled. We present a 32-year-old newly diagnosed T1DM patient who presented with diabetic ketoacidosis (DKA) and HbA1C of 12.7%. She was on basal bolus insulin regimen for the first 4 months after diagnosis. Later, she stopped taking insulin and other anti-diabetic medications due to compliance and logistical issues. Eleven months after diagnosis, her HbA1C spontaneously improved to 5.6%. Currently (14 months after T1DM diagnosis), she is still in complete remission, not requiring insulin therapy.
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