Evidence map›Paper›PMID 26485598›Full record

Trial reportOtology & neurotology : official publication of the American Otological Society, American Neurotology Society [and] European Academy of Otology and Neurotology2015

Utility of an Abbreviated Dizziness Questionnaire to Differentiate Between Causes of Vertigo and Guide Appropriate Referral: A Multicenter Prospective Blinded Study.

Lauren T Roland, Dorina Kallogjeri, Belinda C Sinks, Steven D Rauch, Neil T Shepard, Judith A White, Joel A Goebel

Open access · greenAbstract readClinical TrialMulticenter Study
In one paragraph

Trial report in Otology & neurotology : official publication of the American Otological Society, American Neurotology Society [and] European Academy of Otology and Neurotology, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed
1.3field-weighted citation impact, top 20% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

14 citing papers in PubMed, 29 citations in OpenAlex.

  1. A digital neurotology history: Characteristics and inter-rater reliability.European archives of oto-rhino-laryngology : official journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery · 2026
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  8. Efficient Use of Vestibular Testing.Otolaryngologic clinics of North America · 2021
    Review
  9. Article
  10. A Chair-based Abbreviated Repositioning Maneuver (ChARM) for fast treatment of posterior BPPV.European archives of oto-rhino-laryngology : official journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery · 2019
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 4 institutions in 1 country.

Lauren T Roland*Department of Otolaryngology - Head and Neck Surgery, Washington University in St Louis School of Medicine, St Louis, Missouri †Department of Otolaryngology, Massachusetts Eye and Ear Infirmary, Boston, Massachusetts ‡Division of Audiology, Mayo Clinic, Rochester, Minnesota §Section of Vestibular and Balance Disorders, Head and Neck Institute, The Cleveland Clinic, Cleveland, Ohio, U.S.A.
Dorina Kallogjeri
Belinda C Sinks
Steven D Rauch
Neil T Shepard
Judith A White
Joel A Goebel
Washington University in St. Louis · USCleveland Clinic · USHarvard University Press · USMayo Clinic · US

Funding

Washington University Center for Cellular ImagingP30CA091842 · NCI · WASHINGTON UNIVERSITY · PI TIMOTHY J. EBERLEIN · 2001 to 2026
$128.0M
Washington University Institute of Clinical and Translational SciencesUL1TR000448 · NCATS · WASHINGTON UNIVERSITY · PI EVANOFF, BRADLEY A · 2012 to 2016
$41.4M
Sensory Function CoreP30DC004665 · NIDCD · WASHINGTON UNIVERSITY · PI FADDIS, BRIAN T · 2001 to 2015
$8.0M
DEVELOPMENT OF CLINICIAN/RESEARCHERS IN ACADEMIC ENTT32DC000022 · NIDCD · WASHINGTON UNIVERSITY · PI PICCIRILLO, JAY F. · 1989 to 2022
$5.6M
NCATS NIH HHS UL1 TR000448NCATS NIH HHS UL1TR000448NCI NIH HHS P30 CA091842NIDCD NIH HHS P30 DC004665NIDCD NIH HHS P30DC04665NIDCD NIH HHS T32 DC000022NIDCD NIH HHS T32 DC00022
6 · The paper itself

Abstract

objectiveTest performance of a focused dizziness questionnaire's ability to discriminate between peripheral and nonperipheral causes of vertigo. STUDY

designProspective multicenter.

settingFour academic centers with experienced balance specialists. PATIENTS: New dizzy patients.

interventionsA 32-question survey was given to participants. Balance specialists were blinded and a diagnosis was established for all participating patients within 6 months. MAIN OUTCOMES: Multinomial logistic regression was used to evaluate questionnaire performance in predicting final diagnosis and differentiating between peripheral and nonperipheral vertigo. Univariate and multivariable stepwise logistic regression were used to identify questions as significant predictors of the ultimate diagnosis. C-index was used to evaluate performance and discriminative power of the multivariable models.

resultsIn total, 437 patients participated in the study. Eight participants without confirmed diagnoses were excluded and 429 were included in the analysis. Multinomial regression revealed that the model had good overall predictive accuracy of 78.5% for the final diagnosis and 75.5% for differentiating between peripheral and nonperipheral vertigo. Univariate logistic regression identified significant predictors of three main categories of vertigo: peripheral, central, and other. Predictors were entered into forward stepwise multivariable logistic regression. The discriminative power of the final models for peripheral, central, and other causes was considered good as measured by c-indices of 0.75, 0.7, and 0.78, respectively.

conclusionThis multicenter study demonstrates a focused dizziness questionnaire can accurately predict diagnosis for patients with chronic/relapsing dizziness referred to outpatient clinics. Additionally, this survey has significant capability to differentiate peripheral from nonperipheral causes of vertigo and may, in the future, serve as a screening tool for specialty referral. Clinical utility of this questionnaire to guide specialty referral is discussed.

Indexed as

Surveys and QuestionnairesAgedDizzinessFemaleHumansLogistic ModelsMaleMiddle AgedProspective StudiesVertigo

Identifiers

PMID26485598
PMCPMC4692465
OpenAlexW1810713633

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.